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Eradication of HIV-1 latent reservoirs through therapeutic vaccination

Overview of attention for article published in AIDS Research and Therapy, September 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (72nd percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

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9 X users

Citations

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22 Dimensions

Readers on

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78 Mendeley
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Title
Eradication of HIV-1 latent reservoirs through therapeutic vaccination
Published in
AIDS Research and Therapy, September 2017
DOI 10.1186/s12981-017-0177-4
Pubmed ID
Authors

Joshua Pankrac, Katja Klein, Jamie F. S. Mann

Abstract

Despite the significant success of combination anti-retroviral therapy to reduce HIV viremia and save lives, HIV-1 infection remains a lifelong infection that must be appropriately managed. Advances in the understanding of the HIV infection process and insights from vaccine development in other biomedical fields such as cancer, imaging, and genetic engineering have fueled rapid advancements in HIV cure research. In the last few years, several studies have focused on the development of "Kick and Kill" therapies to reverse HIV latency and kick start viral translational activity. This has been done with the aim that concomitant anti-retroviral treatment and the elicited immune responses will prevent de novo infections while eradicating productively infected cells. In this review, we describe our perspective on HIV cure and the new approaches we are undertaking to eradicate the established pro-viral reservoir.

X Demographics

X Demographics

The data shown below were collected from the profiles of 9 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 78 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 19%
Student > Bachelor 15 19%
Student > Master 13 17%
Researcher 11 14%
Other 4 5%
Other 8 10%
Unknown 12 15%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 14 18%
Immunology and Microbiology 14 18%
Medicine and Dentistry 12 15%
Agricultural and Biological Sciences 7 9%
Nursing and Health Professions 5 6%
Other 11 14%
Unknown 15 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2018.
All research outputs
#5,553,859
of 23,001,641 outputs
Outputs from AIDS Research and Therapy
#140
of 556 outputs
Outputs of similar age
#86,820
of 315,999 outputs
Outputs of similar age from AIDS Research and Therapy
#5
of 18 outputs
Altmetric has tracked 23,001,641 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 556 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,999 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.