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Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice

Overview of attention for article published in BMC Neuroscience, July 2014
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1 Facebook page
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1 Redditor

Citations

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38 Mendeley
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Title
Chronic nicotine pretreatment is sufficient to upregulate α4* nicotinic receptors and increase oral nicotine self-administration in mice
Published in
BMC Neuroscience, July 2014
DOI 10.1186/1471-2202-15-89
Pubmed ID
Authors

Anthony Renda, Raad Nashmi

Abstract

Understanding the underlying causes of nicotine addiction will require a multidisciplinary approach examining the key molecular, cellular and neuronal circuit functional changes that drive escalating levels of nicotine self-administration. In this study, we examined whether mice pretreated with chronic nicotine, at a dosing regimen that results in maximal nicotinic acetylcholine receptor (nAChR) upregulation, would display evidence of nicotine-dependent behaviour during nicotine self-administration.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 18%
Student > Bachelor 6 16%
Researcher 6 16%
Student > Master 5 13%
Professor > Associate Professor 3 8%
Other 6 16%
Unknown 5 13%
Readers by discipline Count As %
Neuroscience 10 26%
Agricultural and Biological Sciences 7 18%
Medicine and Dentistry 7 18%
Psychology 2 5%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Other 3 8%
Unknown 8 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 July 2014.
All research outputs
#18,375,064
of 22,758,963 outputs
Outputs from BMC Neuroscience
#879
of 1,242 outputs
Outputs of similar age
#163,610
of 228,925 outputs
Outputs of similar age from BMC Neuroscience
#27
of 36 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,242 research outputs from this source. They receive a mean Attention Score of 4.3. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,925 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 36 others from the same source and published within six weeks on either side of this one. This one is in the 5th percentile – i.e., 5% of its contemporaries scored the same or lower than it.