Title |
Direct association between pharyngeal viral secretion and host cytokine response in severe pandemic influenza
|
---|---|
Published in |
BMC Infectious Diseases, August 2011
|
DOI | 10.1186/1471-2334-11-232 |
Pubmed ID | |
Authors |
Raquel Almansa, Andres Anton, Paula Ramirez, Ignacio Martin-Loeches, David Banner, Tomás Pumarola, Luoling Xu, Jesús Blanco, Longsi Ran, Guillermo Lopez-Campos, Fernando Martin-Sanchez, Lorenzo Socias, Ana Loza, David Andaluz, Enrique Maravi, Mónica Gordón, Maria C Gallegos, Victoria Fernandez, Cristobal León, Pedro Merino, Maria Ángeles Marcos, Francisco Gandía, Felipe Bobillo, Salvador Resino, Jose Mª Eiros, Carmen Castro, Paula Mateo, Milagros Gonzalez-Rivera, Jordi Rello, Raul Ortiz de Lejarazu, David J Kelvin, Jesus F Bermejo-Martin |
Abstract |
Severe disease caused by 2009 pandemic influenza A/H1N1virus is characterized by the presence of hypercytokinemia. The origin of the exacerbated cytokine response is unclear. As observed previously, uncontrolled influenza virus replication could strongly influence cytokine production. The objective of the present study was to evaluate the relationship between host cytokine responses and viral levels in pandemic influenza critically ill patients. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Japan | 1 | 2% |
Unknown | 44 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 12 | 27% |
Student > Ph. D. Student | 8 | 18% |
Professor > Associate Professor | 5 | 11% |
Student > Bachelor | 3 | 7% |
Professor | 3 | 7% |
Other | 9 | 20% |
Unknown | 5 | 11% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 13 | 29% |
Agricultural and Biological Sciences | 11 | 24% |
Biochemistry, Genetics and Molecular Biology | 5 | 11% |
Immunology and Microbiology | 5 | 11% |
Social Sciences | 1 | 2% |
Other | 3 | 7% |
Unknown | 7 | 16% |