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Angioleiomyoma, a rare intracranial tumor: 3 case report and a literature review

Overview of attention for article published in World Journal of Surgical Oncology, July 2014
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Title
Angioleiomyoma, a rare intracranial tumor: 3 case report and a literature review
Published in
World Journal of Surgical Oncology, July 2014
DOI 10.1186/1477-7819-12-216
Pubmed ID
Authors

Lijun Sun, Yan Zhu, Hong Wang

Abstract

Three cases of intracranial angioleiomyoma (ALM) in our neurosurgery center are reported in detail. ALM is a benign soft tissue tumor comprised of mature smooth muscle cells and a prominent vascular component, which is extremely rare as a primary intracranial lesion. Altogether, only 12 cases were recorded in the literature to date, to the best of our knowledge. Case 1 is the second report of intra-sella ALM, a 51-year-old woman presented with visual deterioration for 2 months. An MRI showed an intra-sella 3-cm tumor, partially flame-like, enhanced with gadolinium. Using microscopic endonasal transsphenoidal approach, the tumor was completely resected with great difficulty. At 11 days post-surgery, she died of a sudden catastrophic nasal hemorrhage . An angiography revealed a pseudo-aneurysm of ICA (internal carotid artery). Case 2 is a 49-year-old man who presented with weakness of the lower limbs for 1 year. A large subtentorial mass was found affixed to the torcular and straight sinus, which was partially flame-like, dramatically enhanced as in case 1. Case 3 is that of a77-year-old man. An ALM mass was revealed in the diploe of left temporal bone, and had eroded the inner table. Immunohistochemical workup confirmed the diagnosis of angioleiomyoma in all 3 cases. The radiology, operation, and complication of surgery in each case were discussed. In conclusion, intracranial ALMs are extremely rare, usually located ex-neuro axis (such as in our cases), in the sella, in posterior fossa, or in the skull. Magnetic resonance imaging (MRI) revealed a special feature of flame-like partial enhancement that may be helpful to distinguish ALM from pituitary tumors or meningiomas, and should result in the consideration of this rare tumor entity early on in the diagnostic process. A definitive diagnosis depends on histological analyses. The resection of ALM in certain locations is difficult and risky because of the rich blood supply.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 42 100%

Demographic breakdown

Readers by professional status Count As %
Other 7 17%
Student > Doctoral Student 5 12%
Student > Bachelor 4 10%
Student > Ph. D. Student 3 7%
Researcher 3 7%
Other 10 24%
Unknown 10 24%
Readers by discipline Count As %
Medicine and Dentistry 23 55%
Neuroscience 3 7%
Agricultural and Biological Sciences 2 5%
Unknown 14 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 May 2023.
All research outputs
#20,655,488
of 25,373,627 outputs
Outputs from World Journal of Surgical Oncology
#1,099
of 2,145 outputs
Outputs of similar age
#177,205
of 241,798 outputs
Outputs of similar age from World Journal of Surgical Oncology
#33
of 61 outputs
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