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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Heat shock protein 70 down-regulates the production of toll-like receptor-induced pro-inflammatory cytokines by a heat shock factor-1/constitutive heat shock element-binding factor-dependent mechanism
|
|---|---|
| Published in |
Journal of Inflammation, July 2014
|
| DOI | 10.1186/1476-9255-11-19 |
| Pubmed ID | |
| Authors |
Eduardo Ferat-Osorio, Aldair Sánchez-Anaya, Mireille Gutiérrez-Mendoza, Ilka Boscó-Gárate, Isabel Wong-Baeza, Rodolfo Pastelin-Palacios, Gustavo Pedraza-Alva, Laura C Bonifaz, Pedro Cortés-Reynosa, Eduardo Pérez-Salazar, Lourdes Arriaga-Pizano, Constantino López-Macías, Yvonne Rosenstein, Armando Isibasi |
| Abstract |
Heat shock protein 70 (Hsp70) is an intracellular chaperone protein with regulatory and cytoprotective functions. Hsp70 can also be found in the extracellular milieu, as a result of active secretion or passive release from damaged cells. The role of extracellular Hsp70 is not fully understood. Some studies report that it activates monocytes, macrophages and dendritic cells through innate immune receptors (such as Toll-like receptors, TLRs), while others report that Hsp70 is a negative regulator of the inflammatory response. In order to address this apparent inconsistency, in this study we evaluated the response of human monocytes to a highly purified recombinant Hsp70. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Science communicators (journalists, bloggers, editors) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 83 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Indonesia | 1 | 1% |
| Mexico | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 80 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 15 | 18% |
| Student > Master | 11 | 13% |
| Student > Bachelor | 9 | 11% |
| Professor | 6 | 7% |
| Student > Doctoral Student | 6 | 7% |
| Other | 18 | 22% |
| Unknown | 18 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 17 | 20% |
| Agricultural and Biological Sciences | 15 | 18% |
| Biochemistry, Genetics and Molecular Biology | 13 | 16% |
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 4% |
| Immunology and Microbiology | 3 | 4% |
| Other | 13 | 16% |
| Unknown | 19 | 23% |
Attention Score in Context
This research output has an Altmetric Attention Score of 19. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 August 2023.
All research outputs
#1,891,820
of 25,371,288 outputs
Outputs from Journal of Inflammation
#10
of 425 outputs
Outputs of similar age
#18,516
of 240,976 outputs
Outputs of similar age from Journal of Inflammation
#1
of 7 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 425 research outputs from this source. They receive a mean Attention Score of 4.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 240,976 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them