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Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci

Overview of attention for article published in Epigenetics & Chromatin, April 2014
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2 X users

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236 Mendeley
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Title
Three-dimensional super-resolution microscopy of the inactive X chromosome territory reveals a collapse of its active nuclear compartment harboring distinct Xist RNA foci
Published in
Epigenetics & Chromatin, April 2014
DOI 10.1186/1756-8935-7-8
Pubmed ID
Authors

Daniel Smeets, Yolanda Markaki, Volker J Schmid, Felix Kraus, Anna Tattermusch, Andrea Cerase, Michael Sterr, Susanne Fiedler, Justin Demmerle, Jens Popken, Heinrich Leonhardt, Neil Brockdorff, Thomas Cremer, Lothar Schermelleh, Marion Cremer

Abstract

A Xist RNA decorated Barr body is the structural hallmark of the compacted inactive X territory in female mammals. Using super-resolution three-dimensional structured illumination microscopy (3D-SIM) and quantitative image analysis, we compared its ultrastructure with active chromosome territories (CTs) in human and mouse somatic cells, and explored the spatio-temporal process of Barr body formation at onset of inactivation in early differentiating mouse embryonic stem cells (ESCs).

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 236 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 3 1%
United Kingdom 3 1%
Germany 2 <1%
France 2 <1%
Canada 1 <1%
Poland 1 <1%
Unknown 224 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 61 26%
Researcher 43 18%
Student > Bachelor 35 15%
Student > Master 21 9%
Professor 11 5%
Other 31 13%
Unknown 34 14%
Readers by discipline Count As %
Agricultural and Biological Sciences 87 37%
Biochemistry, Genetics and Molecular Biology 72 31%
Physics and Astronomy 11 5%
Engineering 7 3%
Computer Science 5 2%
Other 18 8%
Unknown 36 15%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 August 2014.
All research outputs
#17,723,634
of 22,758,963 outputs
Outputs from Epigenetics & Chromatin
#478
of 566 outputs
Outputs of similar age
#156,986
of 227,647 outputs
Outputs of similar age from Epigenetics & Chromatin
#3
of 5 outputs
Altmetric has tracked 22,758,963 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 566 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 12th percentile – i.e., 12% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 227,647 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5 others from the same source and published within six weeks on either side of this one. This one has scored higher than 2 of them.