Title |
Dysautonomia, fibromyalgia and reflex dystrophy
|
---|---|
Published in |
Arthritis Research & Therapy, July 2007
|
DOI | 10.1186/ar2212 |
Pubmed ID | |
Authors |
Jean Eisinger |
Abstract |
Autonomic nervous system dysfunction observed in fibromyalgia, characterized without exception by a sympathetic hyperactivity and hyporeactivity, has been reported. However, several studies demonstrated reduced levels of norepinephrine and neuropeptide Y at rest and after tilt table in some patients, which was improved by beta-stimulating agents. These findings support heterogeneity in fibromyalgia-associated dysautonomia. Fibromyalgia could be a generalized sympathetic dystrophy since both conditions are activated by trauma and partly linked to sympathetic mechanisms. Yet they differ on several points: hormonal and neurochemical abnormalities are observed in fibromyalgia whereas activation by peripheral trauma and hyperosteolysis are observed in reflex sympathetic dystrophy. |
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Brazil | 1 | 4% |
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Readers by professional status | Count | As % |
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Other | 5 | 18% |
Researcher | 4 | 14% |
Student > Postgraduate | 3 | 11% |
Student > Bachelor | 2 | 7% |
Other | 7 | 25% |
Unknown | 2 | 7% |
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Social Sciences | 2 | 7% |
Other | 2 | 7% |
Unknown | 4 | 14% |