Title |
The combination of stem cells and tissue engineering: an advanced strategy for blood vessels regeneration and vascular disease treatment
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Published in |
Stem Cell Research & Therapy, September 2017
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DOI | 10.1186/s13287-017-0642-y |
Pubmed ID | |
Authors |
Ying Wang, Pei Yin, Guang-Liang Bian, Hao-Yue Huang, Han Shen, Jun-Jie Yang, Zi-Ying Yang, Zhen-Ya Shen |
Abstract |
Over the past years, vascular diseases have continued to threaten human health and increase financial burdens worldwide. Transplantation of allogeneic and autologous blood vessels is the most convenient treatment. However, it could not be applied generally due to the scarcity of donors and the patient's condition. Developments in tissue engineering are contributing greatly with regard to this urgent need for blood vessels. Tissue engineering-derived blood vessels are promising alternatives for patients with aortic dissection/aneurysm. The aim of this review is to show the importance of advances in biomaterials development for the treatment of vascular disease. We also provide a comprehensive overview of the current status of tissue reconstruction from stem cells and transplantable cellular scaffold constructs, focusing on the combination of stem cells and tissue engineering for blood vessel regeneration and vascular disease treatment. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 110 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 23 | 21% |
Student > Ph. D. Student | 17 | 15% |
Student > Master | 16 | 15% |
Researcher | 12 | 11% |
Student > Doctoral Student | 7 | 6% |
Other | 9 | 8% |
Unknown | 26 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Biochemistry, Genetics and Molecular Biology | 22 | 20% |
Engineering | 18 | 16% |
Medicine and Dentistry | 14 | 13% |
Agricultural and Biological Sciences | 6 | 5% |
Chemical Engineering | 4 | 4% |
Other | 13 | 12% |
Unknown | 33 | 30% |