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Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial–a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within…

Overview of attention for article published in Trials, May 2014
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Title
Benefits of Aldosterone Receptor Antagonism in Chronic Kidney Disease (BARACK D) trial–a multi-centre, prospective, randomised, open, blinded end-point, 36-month study of 2,616 patients within primary care with stage 3b chronic kidney disease to compare the efficacy of spironolactone 25 mg once daily in addition to routine care on mortality and cardiovascular outcomes versus routine care alone: study protocol for a randomized controlled trial
Published in
Trials, May 2014
DOI 10.1186/1745-6215-15-160
Pubmed ID
Authors

Nathan R Hill, Daniel Lasserson, Ben Thompson, Rafael Perera-Salazar, Jane Wolstenholme, Peter Bower, Thomas Blakeman, David Fitzmaurice, Paul Little, Gene Feder, Nadeem Qureshi, Maarten Taal, Jonathan Townend, Charles Ferro, Richard McManus, FD Richard Hobbs

Abstract

Chronic kidney disease (CKD) is common and increasing in prevalence. Cardiovascular disease (CVD) is a major cause of morbidity and death in CKD, though of a different phenotype to the general CVD population. Few therapies have proved effective in modifying the increased CVD risk or rate of renal decline in CKD. There are accumulating data that aldosterone receptor antagonists (ARA) may offer cardio-protection and delay renal impairment in patients with the CV phenotype in CKD. The use of ARA in CKD has therefore been increasingly advocated. However, no large study of ARA with renal or CVD outcomes is underway.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
Unknown 64 98%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 10 15%
Student > Master 7 11%
Researcher 6 9%
Student > Ph. D. Student 5 8%
Student > Doctoral Student 4 6%
Other 11 17%
Unknown 22 34%
Readers by discipline Count As %
Medicine and Dentistry 22 34%
Nursing and Health Professions 9 14%
Pharmacology, Toxicology and Pharmaceutical Science 2 3%
Psychology 2 3%
Agricultural and Biological Sciences 1 2%
Other 5 8%
Unknown 24 37%