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AurkA inhibitors enhance the effects of B-RAF and MEK inhibitors in melanoma treatment

Overview of attention for article published in Journal of Translational Medicine, July 2014
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Title
AurkA inhibitors enhance the effects of B-RAF and MEK inhibitors in melanoma treatment
Published in
Journal of Translational Medicine, July 2014
DOI 10.1186/s12967-014-0216-z
Pubmed ID
Authors

Emilia Caputo, Roberta Miceli, Maria Letizia Motti, Rosarita Taté, Federica Fratangelo, Gerardo Botti, Nicola Mozzillo, Maria Vincenza Carriero, Ernesta Cavalcanti, Giuseppe Palmieri, Gennaro Ciliberto, Giuseppe Pirozzi, Paolo Antonio Ascierto

Abstract

Aurora kinase A (AurkA) is over-expressed in melanoma and its inhibition has been observed to limit tumor growth, suggesting a potential role in melanoma treatment.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Denmark 1 2%
Slovenia 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 26%
Researcher 6 14%
Student > Bachelor 5 12%
Student > Master 5 12%
Student > Postgraduate 3 7%
Other 3 7%
Unknown 9 21%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 10 24%
Medicine and Dentistry 10 24%
Agricultural and Biological Sciences 9 21%
Psychology 1 2%
Pharmacology, Toxicology and Pharmaceutical Science 1 2%
Other 2 5%
Unknown 9 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 July 2014.
All research outputs
#14,783,222
of 22,759,618 outputs
Outputs from Journal of Translational Medicine
#1,972
of 3,979 outputs
Outputs of similar age
#125,521
of 228,346 outputs
Outputs of similar age from Journal of Translational Medicine
#28
of 63 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,979 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 44th percentile – i.e., 44% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,346 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.