Title |
Molecular subtyping of metastatic melanoma based on cell ganglioside metabolism profiles
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Published in |
BMC Cancer, August 2014
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DOI | 10.1186/1471-2407-14-560 |
Pubmed ID | |
Authors |
Cristina Tringali, Ilaria Silvestri, Francesca Testa, Paola Baldassari, Luigi Anastasia, Roberta Mortarini, Andrea Anichini, Alejandro López-Requena, Guido Tettamanti, Bruno Venerando |
Abstract |
In addition to alterations concerning the expression of oncogenes and onco-suppressors, melanoma is characterized by the presence of distinctive gangliosides (sialic acid carrying glycosphingolipids). Gangliosides strongly control cell surface dynamics and signaling; therefore, it could be assumed that these alterations are linked to modifications of cell behavior acquired by the tumor. On these bases, this work investigated the correlations between melanoma cell ganglioside metabolism profiles and the biological features of the tumor and the survival of patients. |
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Researcher | 7 | 24% |
Student > Ph. D. Student | 7 | 24% |
Student > Master | 3 | 10% |
Professor | 2 | 7% |
Other | 1 | 3% |
Other | 3 | 10% |
Unknown | 6 | 21% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 6 | 21% |
Immunology and Microbiology | 4 | 14% |
Medicine and Dentistry | 3 | 10% |
Agricultural and Biological Sciences | 2 | 7% |
Psychology | 2 | 7% |
Other | 4 | 14% |
Unknown | 8 | 28% |