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Lots of autoantibodies equal lupus?

Overview of attention for article published in Arthritis Research & Therapy, January 2013
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Citations

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18 Mendeley
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Title
Lots of autoantibodies equal lupus?
Published in
Arthritis Research & Therapy, January 2013
DOI 10.1186/ar4126
Pubmed ID
Authors

Martin Aringer, Edward Vital

Abstract

Autoantibodies may be found years before an autoimmune disease becomes clinically apparent. For systemic lupus erythematosus (SLE), those to RNA-binding proteins, to phospholipids, and to double-stranded DNA, in particular, have been found in sera of SLE patients years before the diagnosis was made. New data now show in an unbiased way that, in patients with early SLE, no single antibody class or specificity is associated with progression to SLE. Rather, an increasing number of autoantibody specificities, such as to thyroid antigens, was observed in patients progressing. This points to more generalized B cell autoreactivity during progression to SLE, underlying lupus disease manifestations.

Mendeley readers

The data shown below were compiled from readership statistics for 18 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Sweden 1 6%
Germany 1 6%
Unknown 16 89%

Demographic breakdown

Readers by professional status Count As %
Researcher 4 22%
Student > Doctoral Student 3 17%
Other 2 11%
Student > Bachelor 2 11%
Student > Ph. D. Student 2 11%
Other 5 28%
Readers by discipline Count As %
Medicine and Dentistry 9 50%
Agricultural and Biological Sciences 4 22%
Immunology and Microbiology 2 11%
Biochemistry, Genetics and Molecular Biology 2 11%
Unknown 1 6%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 August 2014.
All research outputs
#3,282,603
of 4,100,542 outputs
Outputs from Arthritis Research & Therapy
#805
of 949 outputs
Outputs of similar age
#81,804
of 102,560 outputs
Outputs of similar age from Arthritis Research & Therapy
#27
of 31 outputs
Altmetric has tracked 4,100,542 research outputs across all sources so far. This one is in the 2nd percentile – i.e., 2% of other outputs scored the same or lower than it.
So far Altmetric has tracked 949 research outputs from this source. They receive a mean Attention Score of 3.3. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 102,560 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 31 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.