Title |
Eradication of scrapie with selective breeding: are we nearly there?
|
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Published in |
BMC Veterinary Research, May 2010
|
DOI | 10.1186/1746-6148-6-24 |
Pubmed ID | |
Authors |
Marielle B Melchior, Jack J Windig, Thomas J Hagenaars, Alex Bossers, Aart Davidse, Fred G van Zijderveld |
Abstract |
Following EU decision 2003/100/EC Member States have recently implemented sheep breeding programmes to reduce the prevalence of sheep with TSE susceptible prion genotypes. The present paper investigates the progress of the breeding programme in the Netherlands. The PrP genotype frequencies were monitored through time using two sets of random samples: one set covers the years 2005 to 2008 and is taken from national surveillance programme; the other is taken from 168 random sheep farms in 2007. The data reveal that although the level of compliance to the breeding programme has been high, the frequency of susceptible genotypes varies substantially between farms. The 168 sheep farms are a subset of 689 farms participating in a postal survey inquiring about management and breeding strategies. This survey aimed to identify how much these strategies varied between farms, in order to inform assessment of the expected future progress towards eradication of classical scrapie. |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Canada | 1 | 3% |
Unknown | 28 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 6 | 21% |
Researcher | 5 | 17% |
Student > Doctoral Student | 2 | 7% |
Student > Bachelor | 2 | 7% |
Other | 2 | 7% |
Other | 5 | 17% |
Unknown | 7 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 8 | 28% |
Biochemistry, Genetics and Molecular Biology | 8 | 28% |
Medicine and Dentistry | 3 | 10% |
Veterinary Science and Veterinary Medicine | 1 | 3% |
Unspecified | 1 | 3% |
Other | 1 | 3% |
Unknown | 7 | 24% |