Title |
Beneficial effects of the olive oil phenolic components oleuropein and hydroxytyrosol: focus on protection against cardiovascular and metabolic diseases
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Published in |
Journal of Translational Medicine, August 2014
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DOI | 10.1186/s12967-014-0219-9 |
Pubmed ID | |
Authors |
Stefania Bulotta, Marilena Celano, Saverio Massimo Lepore, Tiziana Montalcini, Arturo Pujia, Diego Russo |
Abstract |
The overall health beneficial action of olive oil phenolic components is well established. Recent studies have elucidated the biological effects of two isolated compounds, namely oleuropein and hydroxytyrosol, with particular attention on their antioxidant activity. Thus, a protective action has been demonstrated in preclinical studies against several diseases, especially cardiovascular and metabolic disorders. The present review will describe the biological effects of oleuropein and hydroxytyrosol, with particular attention on the molecular mechanism underlying the protective action on cardiovascular and metabolic alterations, as demonstrated by in vitro and in vivo experimental studies performed with the isolated compounds. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 22% |
Turkey | 1 | 11% |
Unknown | 6 | 67% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 89% |
Scientists | 1 | 11% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 2 | <1% |
Italy | 1 | <1% |
Greece | 1 | <1% |
United States | 1 | <1% |
Croatia | 1 | <1% |
Unknown | 426 | 99% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 74 | 17% |
Student > Bachelor | 68 | 16% |
Student > Ph. D. Student | 55 | 13% |
Researcher | 44 | 10% |
Student > Doctoral Student | 22 | 5% |
Other | 64 | 15% |
Unknown | 105 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 76 | 18% |
Medicine and Dentistry | 54 | 13% |
Chemistry | 39 | 9% |
Biochemistry, Genetics and Molecular Biology | 30 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 27 | 6% |
Other | 67 | 16% |
Unknown | 139 | 32% |