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Trans-cranial opening of the blood-brain barrier in targeted regions using astereotaxic brain atlas and focused ultrasound energy

Overview of attention for article published in Journal of Therapeutic Ultrasound, August 2014
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2 tweeters

Citations

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74 Mendeley
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Title
Trans-cranial opening of the blood-brain barrier in targeted regions using astereotaxic brain atlas and focused ultrasound energy
Published in
Journal of Therapeutic Ultrasound, August 2014
DOI 10.1186/2050-5736-2-13
Pubmed ID
Authors

Chenchen Bing, Michelle Ladouceur-Wodzak, Clinton R Wanner, John M Shelton, James A Richardson, Rajiv Chopra

Abstract

The blood-brain barrier (BBB) protects the brain by preventing the entry of large molecules; this poses a major obstacle for the delivery of drugs to the brain. A novel technique using focused ultrasound (FUS) energy combined with microbubble contrast agents has been widely used for non-invasive trans-cranial BBB opening. Traditionally, FUS research is conducted with magnetic resonance imaging (MRI) guidance, which is expensive and poses physical limitations due to the magnetic field. A system that could allow researchers to test brain therapies without MR intervention could facilitate and accelerate translational research.

Twitter Demographics

The data shown below were collected from the profiles of 2 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 74 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 1 1%
Unknown 73 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 18 24%
Researcher 18 24%
Student > Master 9 12%
Professor > Associate Professor 5 7%
Student > Bachelor 4 5%
Other 9 12%
Unknown 11 15%
Readers by discipline Count As %
Engineering 21 28%
Medicine and Dentistry 11 15%
Agricultural and Biological Sciences 11 15%
Neuroscience 5 7%
Physics and Astronomy 3 4%
Other 9 12%
Unknown 14 19%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2014.
All research outputs
#17,238,116
of 21,338,015 outputs
Outputs from Journal of Therapeutic Ultrasound
#59
of 75 outputs
Outputs of similar age
#147,703
of 208,681 outputs
Outputs of similar age from Journal of Therapeutic Ultrasound
#1
of 1 outputs
Altmetric has tracked 21,338,015 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 75 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.0. This one is in the 5th percentile – i.e., 5% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 208,681 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 15th percentile – i.e., 15% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them