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PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples

Overview of attention for article published in Epigenetics & Chromatin, August 2014
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  • Above-average Attention Score compared to outputs of the same age and source (53rd percentile)

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2 X users

Citations

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46 Mendeley
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Title
PAT-ChIP coupled with laser microdissection allows the study of chromatin in selected cell populations from paraffin-embedded patient samples
Published in
Epigenetics & Chromatin, August 2014
DOI 10.1186/1756-8935-7-18
Pubmed ID
Authors

Stefano Amatori, Marco Ballarini, Alice Faversani, Elena Belloni, Fulvia Fusar, Silvano Bosari, Pier Giuseppe Pelicci, Saverio Minucci, Mirco Fanelli

Abstract

The recent introduction of pathology tissue-chromatin immunoprecipitation (PAT-ChIP), a technique allowing chromatin immunoprecipitation from formalin-fixed and paraffin-embedded (FFPE) tissues, has expanded the application potential of epigenetic studies in tissue samples. However, FFPE tissue section analysis is strongly limited by tissue heterogeneity, which hinders linking the observed epigenetic events to the corresponding cellular population. Thus, ideally, to take full advantage of PAT-ChIP approaches, procedures able to increase the purity and homogeneity of cell populations from FFPE tissues are required.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 4%
Denmark 1 2%
Unknown 43 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 24%
Student > Ph. D. Student 8 17%
Student > Bachelor 6 13%
Other 6 13%
Professor > Associate Professor 4 9%
Other 8 17%
Unknown 3 7%
Readers by discipline Count As %
Agricultural and Biological Sciences 24 52%
Biochemistry, Genetics and Molecular Biology 9 20%
Medicine and Dentistry 6 13%
Psychology 1 2%
Unknown 6 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2014.
All research outputs
#14,783,222
of 22,759,618 outputs
Outputs from Epigenetics & Chromatin
#424
of 566 outputs
Outputs of similar age
#126,536
of 230,117 outputs
Outputs of similar age from Epigenetics & Chromatin
#5
of 13 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 32nd percentile – i.e., 32% of other outputs scored the same or lower than it.
So far Altmetric has tracked 566 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 21st percentile – i.e., 21% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 230,117 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 13 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 53% of its contemporaries.