Title |
A randomised clinical trial to evaluate the effects of Plantago ovata husk in Parkinson patients: changes in levodopa pharmacokinetics and biochemical parameters
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Published in |
BMC Complementary Medicine and Therapies, August 2014
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DOI | 10.1186/1472-6882-14-296 |
Pubmed ID | |
Authors |
M Nelida Fernandez-Martinez, Luis Hernandez-Echevarria, Matilde Sierra-Vega, M Jose Diez-Liebana, Angela Calle-Pardo, Demetrio Carriedo-Ule, Ana M Sahagún-Prieto, Anna Anguera-Vila, Juan Jose Garcia-Vieitez |
Abstract |
Plantago ovata husk therapy could be used in patients with Parkinson disease to reduce the symptoms of gastrointestinal disorders, but it is important to know whether this compound modifies levodopa pharmacokinetics. The maintenance of constant plasma concentrations of levodopa abolishes the clinical fluctuations in parkinsonian patients. The aim of this randomised clinical trial was to establish the influence of the fiber Plantago ovata husk in the pharmacokinetics of levodopa when administered to Parkinson patients well controlled by their oral medication. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Chile | 2 | 33% |
Canada | 1 | 17% |
United Kingdom | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 5 | 83% |
Science communicators (journalists, bloggers, editors) | 1 | 17% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 66 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Master | 13 | 20% |
Professor | 7 | 11% |
Student > Bachelor | 6 | 9% |
Student > Ph. D. Student | 5 | 8% |
Other | 3 | 5% |
Other | 16 | 24% |
Unknown | 16 | 24% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 11 | 17% |
Agricultural and Biological Sciences | 7 | 11% |
Nursing and Health Professions | 6 | 9% |
Neuroscience | 5 | 8% |
Pharmacology, Toxicology and Pharmaceutical Science | 5 | 8% |
Other | 12 | 18% |
Unknown | 20 | 30% |