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Combination therapy with silibinin, pegylated interferon and ribavirin in a patient with hepatitis C virus genotype 3 reinfection after liver transplantation: a case report

Overview of attention for article published in Journal of Medical Case Reports, July 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (55th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (61st percentile)

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4 X users

Citations

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4 Dimensions

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9 Mendeley
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Title
Combination therapy with silibinin, pegylated interferon and ribavirin in a patient with hepatitis C virus genotype 3 reinfection after liver transplantation: a case report
Published in
Journal of Medical Case Reports, July 2014
DOI 10.1186/1752-1947-8-257
Pubmed ID
Authors

Johanna Knapstein, Marcus A Wörns, Peter R Galle, Tim Zimmermann

Abstract

Hepatitis C virus reinfection occurs universally after liver transplantation with accelerated cirrhosis rates of up to 30% within 5 years after liver transplantation. Management of hepatitis C virus reinfection is complicated by drug interactions and pre-treatment. Dual antiviral therapy with pegylated interferon and ribavirin only reaches sustained virological response rates of approximately 30% after liver transplantation. With the approval of the viral NS3/4A protease and NS5B ribonucleic acid -dependent ribonucleic acid polymerase inhibitors, combination therapy offers new therapeutic options resulting in considerably higher sustained virological response rates in the non-transplant setting. However, silibinin has also shown potent antiviral activity in non-responders to dual therapy.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 9 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 11%
Italy 1 11%
Unknown 7 78%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 3 33%
Librarian 1 11%
Other 1 11%
Student > Ph. D. Student 1 11%
Student > Master 1 11%
Other 1 11%
Unknown 1 11%
Readers by discipline Count As %
Medicine and Dentistry 3 33%
Environmental Science 1 11%
Chemistry 1 11%
Social Sciences 1 11%
Unknown 3 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 August 2014.
All research outputs
#12,783,738
of 22,760,687 outputs
Outputs from Journal of Medical Case Reports
#804
of 3,903 outputs
Outputs of similar age
#102,079
of 228,570 outputs
Outputs of similar age from Journal of Medical Case Reports
#20
of 52 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,903 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,570 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 55% of its contemporaries.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 61% of its contemporaries.