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PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture

Overview of attention for article published in Journal of Nanobiotechnology, January 2010
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Mentioned by

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1 tweeter
facebook
1 Facebook page

Citations

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135 Dimensions

Readers on

mendeley
138 Mendeley
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1 CiteULike
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Title
PVP-coated silver nanoparticles block the transmission of cell-free and cell-associated HIV-1 in human cervical culture
Published in
Journal of Nanobiotechnology, January 2010
DOI 10.1186/1477-3155-8-15
Pubmed ID
Authors

Humberto H Lara, Liliana Ixtepan-Turrent, Elsa N Garza-Treviño, Cristina Rodriguez-Padilla

Abstract

Previous in vitro studies have demonstrated that polyvinylpyrrolidone coated silver nanoparticles (PVP-coated AgNPs) have antiviral activity against HIV-1 at non-cytotoxic concentrations. These particles also demonstrate broad spectrum virucidal activity by preventing the interaction of HIV-1 gp120 and cellular CD4, thereby inhibiting fusion or entry of the virus into the host cell. In this study, we evaluated the antiviral activity of PVP-coated AgNPs as a potential topical vaginal microbicide to prevent transmission of HIV-1 infection using human cervical culture, an in vitro model that simulates in vivo conditions.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 138 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 2 1%
Ireland 1 <1%
Australia 1 <1%
France 1 <1%
South Africa 1 <1%
Bahrain 1 <1%
India 1 <1%
United States 1 <1%
Unknown 129 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 25 18%
Student > Master 22 16%
Researcher 20 14%
Student > Bachelor 13 9%
Student > Postgraduate 11 8%
Other 21 15%
Unknown 26 19%
Readers by discipline Count As %
Agricultural and Biological Sciences 22 16%
Chemistry 17 12%
Materials Science 13 9%
Biochemistry, Genetics and Molecular Biology 11 8%
Medicine and Dentistry 11 8%
Other 32 23%
Unknown 32 23%

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 July 2022.
All research outputs
#16,980,302
of 21,786,000 outputs
Outputs from Journal of Nanobiotechnology
#704
of 1,237 outputs
Outputs of similar age
#93,199
of 113,344 outputs
Outputs of similar age from Journal of Nanobiotechnology
#1
of 1 outputs
Altmetric has tracked 21,786,000 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,237 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 35th percentile – i.e., 35% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 113,344 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them