Title |
HiChIP: a high-throughput pipeline for integrative analysis of ChIP-Seq data
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Published in |
BMC Bioinformatics, August 2014
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DOI | 10.1186/1471-2105-15-280 |
Pubmed ID | |
Authors |
Huihuang Yan, Jared Evans, Mike Kalmbach, Raymond Moore, Sumit Middha, Stanislav Luban, Liguo Wang, Aditya Bhagwate, Ying Li, Zhifu Sun, Xianfeng Chen, Jean-Pierre A Kocher |
Abstract |
Chromatin immunoprecipitation (ChIP) followed by next-generation sequencing (ChIP-Seq) has been widely used to identify genomic loci of transcription factor (TF) binding and histone modifications. ChIP-Seq data analysis involves multiple steps from read mapping and peak calling to data integration and interpretation. It remains challenging and time-consuming to process large amounts of ChIP-Seq data derived from different antibodies or experimental designs using the same approach. To address this challenge, there is a need for a comprehensive analysis pipeline with flexible settings to accelerate the utilization of this powerful technology in epigenetics research. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 3 | 27% |
France | 2 | 18% |
India | 1 | 9% |
Canada | 1 | 9% |
Unknown | 4 | 36% |
Demographic breakdown
Type | Count | As % |
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Scientists | 8 | 73% |
Members of the public | 3 | 27% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United States | 5 | 3% |
United Kingdom | 4 | 3% |
Netherlands | 1 | <1% |
France | 1 | <1% |
Italy | 1 | <1% |
Germany | 1 | <1% |
Japan | 1 | <1% |
Norway | 1 | <1% |
Unknown | 135 | 90% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 39 | 26% |
Researcher | 26 | 17% |
Student > Master | 18 | 12% |
Student > Bachelor | 10 | 7% |
Other | 10 | 7% |
Other | 28 | 19% |
Unknown | 19 | 13% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 55 | 37% |
Biochemistry, Genetics and Molecular Biology | 40 | 27% |
Computer Science | 12 | 8% |
Medicine and Dentistry | 5 | 3% |
Immunology and Microbiology | 3 | 2% |
Other | 13 | 9% |
Unknown | 22 | 15% |