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Vitamin D deficiency and lower TGF-β/IL-17 ratio in a North Indian cohort of pemphigus vulgaris

Overview of attention for article published in BMC Research Notes, August 2014
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Title
Vitamin D deficiency and lower TGF-β/IL-17 ratio in a North Indian cohort of pemphigus vulgaris
Published in
BMC Research Notes, August 2014
DOI 10.1186/1756-0500-7-536
Pubmed ID
Authors

Neha Joshi, Ranjana W Minz, Shashi Anand, Nisha V Parmar, Amrinder J Kanwar

Abstract

Pemphigus vulgaris (PV) is an autoimmune bullous disease caused by acantholysis of keratinocytes due to pathogenic desmoglein-3 autoantibodies. Role of vitamin D has been recently implicated in various autoimmune conditions due to its immunomodulatory effects on innate and adaptive immune responses. One of the key mechanisms of the immune regulation by vitamin D is through its anti-inflammatory effects by suppression of Th17 functions. Thus, vitamin D may be involved in pathogenesis of PV. In this study, the serum vitamin D, IL-17 and TGF-beta levels in PV patients as well as healthy controls were estimated in order to understand the underlying immune mechanism involved in disease pathogenesis.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 30 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 30 100%

Demographic breakdown

Readers by professional status Count As %
Other 5 17%
Student > Postgraduate 5 17%
Student > Doctoral Student 3 10%
Student > Master 2 7%
Student > Ph. D. Student 2 7%
Other 4 13%
Unknown 9 30%
Readers by discipline Count As %
Medicine and Dentistry 16 53%
Agricultural and Biological Sciences 1 3%
Nursing and Health Professions 1 3%
Neuroscience 1 3%
Engineering 1 3%
Other 0 0%
Unknown 10 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 August 2014.
All research outputs
#18,376,056
of 22,760,687 outputs
Outputs from BMC Research Notes
#3,013
of 4,262 outputs
Outputs of similar age
#164,492
of 230,675 outputs
Outputs of similar age from BMC Research Notes
#89
of 126 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,262 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.5. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
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We're also able to compare this research output to 126 others from the same source and published within six weeks on either side of this one. This one is in the 14th percentile – i.e., 14% of its contemporaries scored the same or lower than it.