Title |
Adverse effects of small-volume red blood cell transfusions in the neonatal population
|
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Published in |
Systematic Reviews, August 2014
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DOI | 10.1186/2046-4053-3-92 |
Pubmed ID | |
Authors |
Amy Keir, Sanchita Pal, Marialena Trivella, Lani Lieberman, Jeannie Callum, Nadine Shehata, Simon Stanworth |
Abstract |
Adverse transfusion reactions in the neonatal population are poorly understood and defined. The incidence and pattern of adverse effects due to red blood cell (RBC) transfusion are not well known, and there has been no systematic review of published adverse events. RBC transfusions continue to be linked to the development of morbidities unique to neonates, including chronic lung disease, retinopathy of prematurity, intraventricular haemorrhage and necrotising enterocolitis. Uncertainties about the exact nature of risks alongside benefits of RBC transfusion may contribute to evidence of widespread variation in neonatal RBC transfusion practice.Our review aims to describe clinical adverse effects attributed to small-volume (10-20 mL/kg) RBC transfusions and, where possible, their incidence rates in the neonatal population through the systematic identification of all relevant studies. |
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Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
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Spain | 1 | 4% |
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Unknown | 24 | 92% |
Demographic breakdown
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Student > Master | 4 | 15% |
Researcher | 3 | 12% |
Student > Ph. D. Student | 3 | 12% |
Other | 2 | 8% |
Professor | 2 | 8% |
Other | 3 | 12% |
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Unknown | 9 | 35% |