↓ Skip to main content

Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution

Overview of attention for article published in Biology Direct, June 2007
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)

Mentioned by

blogs
1 blog
twitter
2 X users
patent
2 patents
googleplus
1 Google+ user
f1000
1 research highlight platform

Citations

dimensions_citation
147 Dimensions

Readers on

mendeley
220 Mendeley
citeulike
8 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Neutral genetic drift can alter promiscuous protein functions, potentially aiding functional evolution
Published in
Biology Direct, June 2007
DOI 10.1186/1745-6150-2-17
Pubmed ID
Authors

Jesse D Bloom, Philip A Romero, Zhongyi Lu, Frances H Arnold

Abstract

Many of the mutations accumulated by naturally evolving proteins are neutral in the sense that they do not significantly alter a protein's ability to perform its primary biological function. However, new protein functions evolve when selection begins to favor other, "promiscuous" functions that are incidental to a protein's original biological role. If mutations that are neutral with respect to a protein's primary biological function cause substantial changes in promiscuous functions, these mutations could enable future functional evolution.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 220 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 5 2%
Belgium 2 <1%
Norway 1 <1%
Australia 1 <1%
Netherlands 1 <1%
Canada 1 <1%
Switzerland 1 <1%
Brazil 1 <1%
Poland 1 <1%
Other 0 0%
Unknown 206 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 66 30%
Researcher 55 25%
Student > Master 18 8%
Student > Bachelor 16 7%
Student > Doctoral Student 9 4%
Other 29 13%
Unknown 27 12%
Readers by discipline Count As %
Agricultural and Biological Sciences 81 37%
Biochemistry, Genetics and Molecular Biology 55 25%
Chemistry 28 13%
Engineering 8 4%
Physics and Astronomy 4 2%
Other 14 6%
Unknown 30 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2014.
All research outputs
#2,271,423
of 22,760,687 outputs
Outputs from Biology Direct
#101
of 487 outputs
Outputs of similar age
#4,842
of 68,409 outputs
Outputs of similar age from Biology Direct
#1
of 3 outputs
Altmetric has tracked 22,760,687 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 487 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 68,409 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 3 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them