Title |
Bacterial community composition of chronic periodontitis and novel oral sampling sites for detecting disease indicators
|
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Published in |
Microbiome, August 2014
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DOI | 10.1186/2049-2618-2-32 |
Pubmed ID | |
Authors |
Vaia Galimanas, Michael William Hall, Natasha Singh, Michael David Joseph Lynch, Michael Goldberg, Howard Tenenbaum, Dennis Gerard Cvitkovitch, Josh David Neufeld, Dilani Braziunas Senadheera |
Abstract |
Periodontitis is an infectious and inflammatory disease of polymicrobial etiology that can lead to the destruction of bones and tissues that support the teeth. The management of chronic periodontitis (CP) relies heavily on elimination or at least control of known pathogenic consortia associated with the disease. Until now, microbial plaque obtained from the subgingival (SubG) sites has been the primary focus for bacterial community analysis using deep sequencing. In addition to the use of SubG plaque, here, we investigated whether plaque obtained from supragingival (SupG) and tongue dorsum sites can serve as alternatives for monitoring CP-associated bacterial biomarkers. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
India | 1 | 13% |
China | 1 | 13% |
Australia | 1 | 13% |
United Kingdom | 1 | 13% |
Unknown | 4 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 8 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 3 | 2% |
Portugal | 1 | <1% |
Canada | 1 | <1% |
Unknown | 142 | 97% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 30 | 20% |
Student > Ph. D. Student | 23 | 16% |
Student > Master | 17 | 12% |
Student > Bachelor | 16 | 11% |
Student > Postgraduate | 11 | 7% |
Other | 28 | 19% |
Unknown | 22 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 40 | 27% |
Medicine and Dentistry | 36 | 24% |
Biochemistry, Genetics and Molecular Biology | 15 | 10% |
Immunology and Microbiology | 8 | 5% |
Pharmacology, Toxicology and Pharmaceutical Science | 3 | 2% |
Other | 16 | 11% |
Unknown | 29 | 20% |