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The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial

Overview of attention for article published in Trials, May 2011
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1 news outlet
blogs
1 blog

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130 Mendeley
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Title
The effectiveness of early lens extraction with intraocular lens implantation for the treatment of primary angle-closure glaucoma (EAGLE): study protocol for a randomized controlled trial
Published in
Trials, May 2011
DOI 10.1186/1745-6215-12-133
Pubmed ID
Authors

Augusto Azuara-Blanco, Jennifer M Burr, Claire Cochran, Craig Ramsay, Luke Vale, Paul Foster, David Friedman, Zahidul Quayyum, Jimmy Lai, Winnie Nolan, Tin Aung, Paul Chew, Gladys McPherson, Alison McDonald, John Norrie, Effectiveness in Angle-closure Glaucoma of Lens Extraction (EAGLE) Study Group

Abstract

Glaucoma is the leading cause of irreversible blindness. Although primary open-angle glaucoma is more common, primary angle-closure glaucoma (PACG) is more likely to result in irreversible blindness. By 2020, 5·3 million people worldwide will be blind because of PACG. The current standard care for PACG is a stepped approach of a combination of laser iridotomy surgery (to open the drainage angle) and medical treatment (to reduce intraocular pressure). If these treatments fail, glaucoma surgery (eg, trabeculectomy) is indicated. It has been proposed that, because the lens of the eye plays a major role in the mechanisms leading to PACG, early clear lens extraction will improve glaucoma control by opening the drainage angle. This procedure might reduce the need for drugs and glaucoma surgery, maintain good visual acuity, and improve quality of life compared with standard care.EAGLE aims to evaluate whether early lens extraction improves patient-reported, clinical outcomes, and cost-effectiveness, compared with standard care.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Colombia 1 <1%
Germany 1 <1%
Malaysia 1 <1%
Australia 1 <1%
United Kingdom 1 <1%
Haiti 1 <1%
Unknown 124 95%

Demographic breakdown

Readers by professional status Count As %
Researcher 19 15%
Other 15 12%
Student > Master 13 10%
Student > Postgraduate 12 9%
Student > Ph. D. Student 11 8%
Other 32 25%
Unknown 28 22%
Readers by discipline Count As %
Medicine and Dentistry 69 53%
Agricultural and Biological Sciences 5 4%
Nursing and Health Professions 4 3%
Pharmacology, Toxicology and Pharmaceutical Science 4 3%
Social Sciences 2 2%
Other 9 7%
Unknown 37 28%