Title |
Gene co-expression network analysis in Rhodobacter capsulatus and application to comparative expression analysis of Rhodobacter sphaeroides
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Published in |
BMC Genomics, August 2014
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DOI | 10.1186/1471-2164-15-730 |
Pubmed ID | |
Authors |
Lourdes Peña-Castillo, Ryan G Mercer, Anastasia Gurinovich, Stephen J Callister, Aaron T Wright, Alexander B Westbye, J Thomas Beatty, Andrew S Lang |
Abstract |
The genus Rhodobacter contains purple nonsulfur bacteria found mostly in freshwater environments. Two Rhodobacter species, R. capsulatus and R. sphaeroides, have had their genomes fully sequenced and both have been the subject of transcriptional profiling studies. Gene co-expression networks can be used to identify modules of genes with similar expression profiles. Functional analysis of gene modules can then associate co-expressed genes with biological pathways, and network statistics can determine the degree of module preservation in related networks. In this paper, we constructed an R. capsulatus gene co-expression network, performed functional analysis of identified gene modules, and investigated preservation of these modules in R. capsulatus proteomics data and in R. sphaeroides transcriptomics data. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
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Scientists | 1 | 50% |
Members of the public | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 51 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 14 | 27% |
Other | 5 | 10% |
Researcher | 5 | 10% |
Professor > Associate Professor | 5 | 10% |
Student > Master | 4 | 8% |
Other | 12 | 24% |
Unknown | 6 | 12% |
Readers by discipline | Count | As % |
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Biochemistry, Genetics and Molecular Biology | 16 | 31% |
Agricultural and Biological Sciences | 14 | 27% |
Immunology and Microbiology | 4 | 8% |
Environmental Science | 2 | 4% |
Medicine and Dentistry | 2 | 4% |
Other | 4 | 8% |
Unknown | 9 | 18% |