Title |
Dynamics of tear fluid desiccation on a glass surface: a contribution to tear quality assessment
|
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Published in |
Biological Research, June 2014
|
DOI | 10.1186/0717-6287-47-25 |
Pubmed ID | |
Authors |
Leonidas Traipe-Castro, Daniela Salinas-Toro, Daniela López, Mario Zanolli, Miguel Srur, Felipe Valenzuela, Aníbal Cáceres, Héctor Toledo-Araya, Remigio López-Solís |
Abstract |
Fern-like crystalloids form when a microvolume of tear is allowed to dry out at ambient conditions on a glass surface. Presence of crystalloids in tear "microdesiccates" is used to evaluate patients with Dry-Eye disease. This study aims to examine morphologically the desiccation process of normal tear fluid and to identify changes associated with accelerated tear evaporation. Tear microdesiccates from healthy (Non-Dry Eye) and Dry Eye subjects were produced at ambient conditions. Microdesiccate formation was monitored continuously by dark-field video microscopy. Additionally, accelerated desiccation of tear samples from healthy subjects was conducted under controlled experimental conditions. Particular morphological domains of tear microdesiccates and their progressive appearance during desiccation were compared. |
X Demographics
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Canada | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 25 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 4 | 16% |
Student > Ph. D. Student | 4 | 16% |
Student > Master | 4 | 16% |
Researcher | 3 | 12% |
Other | 3 | 12% |
Other | 4 | 16% |
Unknown | 3 | 12% |
Readers by discipline | Count | As % |
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Medicine and Dentistry | 9 | 36% |
Social Sciences | 2 | 8% |
Nursing and Health Professions | 2 | 8% |
Psychology | 2 | 8% |
Immunology and Microbiology | 1 | 4% |
Other | 6 | 24% |
Unknown | 3 | 12% |