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Synthetic organotelluride compounds induce the reversal of Pdr5p mediated fluconazole resistance in Saccharomyces cerevisiae

Overview of attention for article published in BMC Microbiology, July 2014
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Title
Synthetic organotelluride compounds induce the reversal of Pdr5p mediated fluconazole resistance in Saccharomyces cerevisiae
Published in
BMC Microbiology, July 2014
DOI 10.1186/s12866-014-0201-y
Pubmed ID
Authors

Leandro Figueira Reis de Sá, Fabiano Travanca Toledo, Bruno Artur de Sousa, Augusto César Gonçalves, Ana Claudia Tessis, Edison P Wendler, João V Comasseto, Alcindo A Dos Santos, Antonio Ferreira-Pereira

Abstract

Resistance to fluconazole, a commonly used azole antifungal, is a challenge for the treatment of fungal infections. Resistance can be mediated by overexpression of ABC transporters, which promote drug efflux that requires ATP hydrolysis. The Pdr5p ABC transporter of Saccharomyces cerevisiae is a well-known model used to study this mechanism of antifungal resistance. The present study investigated the effects of 13 synthetic compounds on Pdr5p.

X Demographics

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 7 18%
Student > Ph. D. Student 7 18%
Student > Bachelor 5 13%
Student > Doctoral Student 4 11%
Researcher 3 8%
Other 6 16%
Unknown 6 16%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 7 18%
Chemistry 6 16%
Agricultural and Biological Sciences 5 13%
Social Sciences 3 8%
Immunology and Microbiology 2 5%
Other 6 16%
Unknown 9 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 March 2015.
All research outputs
#17,725,418
of 22,761,738 outputs
Outputs from BMC Microbiology
#1,999
of 3,184 outputs
Outputs of similar age
#155,256
of 229,487 outputs
Outputs of similar age from BMC Microbiology
#27
of 43 outputs
Altmetric has tracked 22,761,738 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,184 research outputs from this source. They receive a mean Attention Score of 4.1. This one is in the 29th percentile – i.e., 29% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 229,487 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 28th percentile – i.e., 28% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 43 others from the same source and published within six weeks on either side of this one. This one is in the 30th percentile – i.e., 30% of its contemporaries scored the same or lower than it.