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Genomic imprinting of IGF2 in marsupials is methylation dependent

Overview of attention for article published in BMC Genomics, May 2008
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (97th percentile)

Mentioned by

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3 news outlets
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1 X user
wikipedia
1 Wikipedia page

Citations

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23 Dimensions

Readers on

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42 Mendeley
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1 CiteULike
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Title
Genomic imprinting of IGF2 in marsupials is methylation dependent
Published in
BMC Genomics, May 2008
DOI 10.1186/1471-2164-9-205
Pubmed ID
Authors

Betty R Lawton, Benjamin R Carone, Craig J Obergfell, Gianni C Ferreri, Christina M Gondolphi, John L VandeBerg, Ikhide Imumorin, Rachel J O'Neill, Michael J O'Neill

Abstract

Parent-specific methylation of specific CpG residues is critical to imprinting in eutherian mammals, but its importance to imprinting in marsupials and, thus, the evolutionary origins of the imprinting mechanism have been the subject of controversy. This has been particularly true for the imprinted Insulin-like Growth Factor II (IGF2), a key regulator of embryonic growth in vertebrates and a focal point of the selective forces leading to genomic imprinting. The presence of the essential imprinting effector, DNMT3L, in marsupial genomes and the demonstration of a differentially methylated region (DMR) in the retrotransposon-derived imprinted gene, PEG10, in tammar wallaby argue for a role for methylation in imprinting, but several studies have found no evidence of parent-specific methylation at other imprinted loci in marsupials.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 42 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 2%
United States 1 2%
Czechia 1 2%
Unknown 39 93%

Demographic breakdown

Readers by professional status Count As %
Researcher 10 24%
Student > Ph. D. Student 9 21%
Student > Master 5 12%
Professor 5 12%
Student > Bachelor 3 7%
Other 8 19%
Unknown 2 5%
Readers by discipline Count As %
Agricultural and Biological Sciences 25 60%
Biochemistry, Genetics and Molecular Biology 5 12%
Medicine and Dentistry 3 7%
Unspecified 2 5%
Neuroscience 2 5%
Other 1 2%
Unknown 4 10%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 31. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 October 2017.
All research outputs
#1,065,831
of 22,763,032 outputs
Outputs from BMC Genomics
#189
of 10,638 outputs
Outputs of similar age
#2,182
of 79,091 outputs
Outputs of similar age from BMC Genomics
#1
of 34 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,638 research outputs from this source. They receive a mean Attention Score of 4.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 79,091 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 34 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 97% of its contemporaries.