↓ Skip to main content

Targeted gene suppression by inducing de novo DNA methylation in the gene promoter

Overview of attention for article published in Epigenetics & Chromatin, August 2014
Altmetric Badge

About this Attention Score

  • Good Attention Score compared to outputs of the same age (68th percentile)
  • High Attention Score compared to outputs of the same age and source (90th percentile)

Mentioned by

twitter
1 X user
patent
1 patent

Citations

dimensions_citation
17 Dimensions

Readers on

mendeley
60 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Targeted gene suppression by inducing de novo DNA methylation in the gene promoter
Published in
Epigenetics & Chromatin, August 2014
DOI 10.1186/1756-8935-7-20
Pubmed ID
Authors

Ai-Niu Ma, Hong Wang, Rui Guo, Yong-Xiang Wang, Wei Li, Jiuwei Cui, Guanjun Wang, Andrew R Hoffman, Ji-Fan Hu

Abstract

Targeted gene silencing is an important approach in both drug development and basic research. However, the selection of a potent suppressor has become a significant hurdle to implementing maximal gene inhibition for this approach. We attempted to construct a 'super suppressor' by combining the activities of two suppressors that function through distinct epigenetic mechanisms.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 60 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 59 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 15 25%
Researcher 15 25%
Student > Master 7 12%
Student > Bachelor 6 10%
Professor > Associate Professor 5 8%
Other 6 10%
Unknown 6 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 21 35%
Biochemistry, Genetics and Molecular Biology 19 32%
Engineering 3 5%
Materials Science 3 5%
Economics, Econometrics and Finance 2 3%
Other 5 8%
Unknown 7 12%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 24 November 2021.
All research outputs
#7,201,896
of 22,763,032 outputs
Outputs from Epigenetics & Chromatin
#301
of 566 outputs
Outputs of similar age
#71,491
of 235,043 outputs
Outputs of similar age from Epigenetics & Chromatin
#1
of 11 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. This one has received more attention than most of these and is in the 67th percentile.
So far Altmetric has tracked 566 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one is in the 45th percentile – i.e., 45% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 235,043 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 90% of its contemporaries.