Title |
Clinical challenge: fatal mucormycotic osteomyelitis caused by Rhizopus microsporus despite aggressive multimodal treatment
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Published in |
BMC Infectious Diseases, September 2014
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DOI | 10.1186/1471-2334-14-488 |
Pubmed ID | |
Authors |
Norbert Harrasser, Ingo J Banke, Matthias Hauschild, Ulrich Lenze, Peter M Prodinger, Andreas Toepfer, Christian Peschel, Rüdiger von Eisenhart-Rothe, Ingo Ringshausen, Mareike Verbeek |
Abstract |
Mucormycosis is an invasive mycotic disease caused by fungi in the zygomycetes class. Although ubiquitous in the environment, zygomycetes are rarely known to cause invasive disease in immunocompromised hosts with a high mortality even under aggressive antifungal and surgical therapy. Clinically, mucormycosis frequently affects the sinus occasionally showing pulmonary or cerebral involvement. However skeletal manifestation with Rhizopus microsporus (RM) osteomyelitis leading to emergency surgical proximal femoral resection with fatal outcome has not been described yet. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 2 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 1 | 50% |
Scientists | 1 | 50% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 29 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 4 | 14% |
Student > Bachelor | 3 | 10% |
Researcher | 3 | 10% |
Student > Postgraduate | 2 | 7% |
Lecturer | 1 | 3% |
Other | 4 | 14% |
Unknown | 12 | 41% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 8 | 28% |
Social Sciences | 2 | 7% |
Immunology and Microbiology | 2 | 7% |
Arts and Humanities | 1 | 3% |
Environmental Science | 1 | 3% |
Other | 2 | 7% |
Unknown | 13 | 45% |