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Induction of integrin α2 in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture

Overview of attention for article published in Molecular Cancer, September 2014
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Citations

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31 Mendeley
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Title
Induction of integrin α2 in a highly bone metastatic human prostate cancer cell line: roles of RANKL and AR under three-dimensional suspension culture
Published in
Molecular Cancer, September 2014
DOI 10.1186/1476-4598-13-208
Pubmed ID
Authors

Shabnam Ziaee, Leland WK Chung

Abstract

Prostate cancer (PCa) bone metastasis can be markedly enhanced by increased receptor activator of NF kappa-B ligand (RANKL) expression in PCa cells. Molecular mechanisms that account for the increased predilection of PCa for bone include increased bone turnover, promotion of PCa cell growth and survival in the bone environment, and recruitment of bystander dormant cells to participate in bone metastasis. The current study tests the hypothesis that PCa cells acquire high adhesion to bone matrix proteins, which controls PCa bone colonization, under the RANKL/RANK and AR axes.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 31 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Poland 1 3%
Egypt 1 3%
Unknown 29 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 32%
Researcher 5 16%
Student > Doctoral Student 4 13%
Student > Bachelor 3 10%
Student > Master 2 6%
Other 1 3%
Unknown 6 19%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 35%
Agricultural and Biological Sciences 5 16%
Medicine and Dentistry 4 13%
Nursing and Health Professions 1 3%
Unknown 10 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 04 February 2015.
All research outputs
#22,756,649
of 25,371,288 outputs
Outputs from Molecular Cancer
#1,678
of 1,918 outputs
Outputs of similar age
#214,404
of 250,134 outputs
Outputs of similar age from Molecular Cancer
#49
of 52 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,918 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.8. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 250,134 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 52 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.