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The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation

Overview of attention for article published in Molecular Cancer, August 2014
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Title
The chemokine receptor CXCR7 interacts with EGFR to promote breast cancer cell proliferation
Published in
Molecular Cancer, August 2014
DOI 10.1186/1476-4598-13-198
Pubmed ID
Authors

Nicole Salazar, Daniel Muñoz, Georgios Kallifatidis, Rajendra K Singh, Mercè Jordà, Bal L Lokeshwar

Abstract

Recent advances have revealed a significant contribution of chemokines and their receptors in tumor growth, survival after chemotherapy, and organ-specific metastasis. The CXC chemokine receptor-7 (CXCR7) is the latest chemokine receptor implicated in cancer. Although over expressed in breast cancer cell lines and tumor tissues, its mechanism of action in breast cancer (BrCa) growth and metastasis is unclear. Studies in other cancers have implicated CXCR7 in cell proliferation, anti-apoptotic activity and cell-cell adhesion. The present study was initiated to examine the pattern of CXCR7 expression and its role in regulation of growth signaling in breast cancer.

X Demographics

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 95 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Brazil 1 1%
Unknown 93 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 24 25%
Student > Bachelor 15 16%
Student > Master 13 14%
Researcher 9 9%
Student > Postgraduate 4 4%
Other 13 14%
Unknown 17 18%
Readers by discipline Count As %
Agricultural and Biological Sciences 26 27%
Biochemistry, Genetics and Molecular Biology 19 20%
Medicine and Dentistry 10 11%
Pharmacology, Toxicology and Pharmaceutical Science 6 6%
Chemistry 5 5%
Other 12 13%
Unknown 17 18%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 September 2014.
All research outputs
#18,378,085
of 22,763,032 outputs
Outputs from Molecular Cancer
#1,288
of 1,719 outputs
Outputs of similar age
#168,522
of 236,627 outputs
Outputs of similar age from Molecular Cancer
#37
of 44 outputs
Altmetric has tracked 22,763,032 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 14th percentile – i.e., 14% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,627 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 16th percentile – i.e., 16% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 6th percentile – i.e., 6% of its contemporaries scored the same or lower than it.