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T-cell activation discriminates subclasses of symptomatic primary humoral immunodeficiency diseases in adults

Overview of attention for article published in BMC Immunology, March 2014
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Title
T-cell activation discriminates subclasses of symptomatic primary humoral immunodeficiency diseases in adults
Published in
BMC Immunology, March 2014
DOI 10.1186/1471-2172-15-13
Pubmed ID
Authors

Marie-Quitterie Picat, Rodolphe Thiébaut, François Lifermann, Xavier Delbrel, Daniel Adoue, Linda Wittkop, Anne-Laure Fauchais, Patrick Rispal, Jean-François Moreau, Jean-François Viallard

Abstract

Symptomatic Primary Humoral Immunodeficiency Diseases (PHID) constitute a highly heterogeneous group of diseases characterized by a shared hypogammaglobulinemia, resulting in increased risk of recurrent or severe infections. Associations have been described with a variety of immunological abnormalities involving B and T-cell differentiation, T-cell activation and innate immunity. However, PHID discrimination remains based on B-lymphocyte abnormalities and other components of the immune system have not been sufficiently taken into account. We carried out unsupervised and supervised methods for classification in a cohort of 81 symptomatic PHID patients to evaluate the relative importance of 23 immunological parameters and to select relevant markers that may be useful for diagnosis and prognosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 23 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 1 4%
Unknown 22 96%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 4 17%
Student > Master 4 17%
Other 3 13%
Researcher 3 13%
Student > Bachelor 2 9%
Other 4 17%
Unknown 3 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 6 26%
Medicine and Dentistry 6 26%
Immunology and Microbiology 4 17%
Sports and Recreations 2 9%
Unknown 5 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 September 2014.
All research outputs
#20,236,620
of 22,763,032 outputs
Outputs from BMC Immunology
#500
of 585 outputs
Outputs of similar age
#189,871
of 221,258 outputs
Outputs of similar age from BMC Immunology
#5
of 8 outputs
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So far Altmetric has tracked 585 research outputs from this source. They receive a mean Attention Score of 3.7. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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