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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Elevation of brain magnesium prevents synaptic loss and reverses cognitive deficits in Alzheimer’s disease mouse model
|
|---|---|
| Published in |
Molecular Brain, September 2014
|
| DOI | 10.1186/s13041-014-0065-y |
| Pubmed ID | |
| Authors |
Wei Li, Jia Yu, Yong Liu, Xiaojie Huang, Nashat Abumaria, Ying Zhu, Xian Huang, Wenxiang Xiong, Chi Ren, Xian-Guo Liu, Dehua Chui, Guosong Liu |
| Abstract |
Profound synapse loss is one of the major pathological hallmarks associated with Alzheimer's disease, which might underlie memory impairment. Our previous work demonstrates that magnesium ion is a critical factor in controlling synapse density/plasticity. Here, we tested whether elevation of brain magnesium, using a recently developed compound (magnesium-L-threonate, MgT), can ameliorate the AD-like pathologies and cognitive deficits in the APPswe/PS1dE9 mice, a transgenic mouse model of Alzheimer's disease. |
X Demographics
The data shown below were collected from the profiles of 78 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Japan | 12 | 15% |
| United States | 5 | 6% |
| Russia | 1 | 1% |
| Germany | 1 | 1% |
| Spain | 1 | 1% |
| Sweden | 1 | 1% |
| Canada | 1 | 1% |
| Brazil | 1 | 1% |
| Unknown | 55 | 71% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 74 | 95% |
| Practitioners (doctors, other healthcare professionals) | 2 | 3% |
| Scientists | 1 | 1% |
| Science communicators (journalists, bloggers, editors) | 1 | 1% |
Mendeley readers
The data shown below were compiled from readership statistics for 127 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Netherlands | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 125 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 27 | 21% |
| Student > Bachelor | 18 | 14% |
| Student > Ph. D. Student | 16 | 13% |
| Student > Master | 15 | 12% |
| Other | 11 | 9% |
| Other | 16 | 13% |
| Unknown | 24 | 19% |
| Readers by discipline | Count | As % |
|---|---|---|
| Neuroscience | 23 | 18% |
| Medicine and Dentistry | 21 | 17% |
| Biochemistry, Genetics and Molecular Biology | 12 | 9% |
| Agricultural and Biological Sciences | 10 | 8% |
| Nursing and Health Professions | 6 | 5% |
| Other | 20 | 16% |
| Unknown | 35 | 28% |
Attention Score in Context
This research output has an Altmetric Attention Score of 78. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 March 2024.
All research outputs
#548,895
of 25,402,889 outputs
Outputs from Molecular Brain
#10
of 1,198 outputs
Outputs of similar age
#5,380
of 257,775 outputs
Outputs of similar age from Molecular Brain
#1
of 22 outputs
Altmetric has tracked 25,402,889 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 97th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,198 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has done particularly well, scoring higher than 99% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 257,775 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 22 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.