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The association between maternal use of folic acid supplements during pregnancy and risk of autism spectrum disorders in children: a meta-analysis

Overview of attention for article published in Molecular Autism, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)

Mentioned by

blogs
2 blogs
twitter
20 tweeters
facebook
1 Facebook page
wikipedia
1 Wikipedia page
googleplus
1 Google+ user

Citations

dimensions_citation
36 Dimensions

Readers on

mendeley
121 Mendeley
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Title
The association between maternal use of folic acid supplements during pregnancy and risk of autism spectrum disorders in children: a meta-analysis
Published in
Molecular Autism, October 2017
DOI 10.1186/s13229-017-0170-8
Pubmed ID
Authors

Meiyun Wang, Kaiqin Li, Dongmei Zhao, Ling Li

Abstract

Previous reviews have been conducted to evaluate the association between maternal use of folic acid supplements during pregnancy and risk of autism spectrum disorders (ASD) in children, with no definitive conclusion. We therefore conducted a more comprehensive meta-analysis to reassess the relationship between folic acid and the risk of ASD. The electronic databases PubMed, Web of Knowledge, and Wanfang Data were carefully searched to find eligible studies as recent as March 2017. A random effects model was used to combine the relative risk (RR) with 95% confidence intervals (CI). Sensitivity analysis and publication bias were conducted. A total of 12 articles with 16 studies comprising 4514 ASD cases were included in this report. It was found that supplementation with folic acid during pregnancy could reduce the risk of ASD [RR = 0.771, 95% CI = 0.641-0.928, I(2)  = 59.7%, Pheterogeneity = 0.001] as compared to those women without folic acid supplementation. The associations were significant among Asian, European, and American populations. In summary, this comprehensive meta-analysis suggested that maternal use of folic acid supplements during pregnancy could significantly reduce the risk of ASD in children regardless of ethnicity, as compared to those women who did not supplement with folic acid.

Twitter Demographics

The data shown below were collected from the profiles of 20 tweeters who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 121 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 121 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 20 17%
Student > Ph. D. Student 18 15%
Student > Bachelor 16 13%
Researcher 15 12%
Other 8 7%
Other 16 13%
Unknown 28 23%
Readers by discipline Count As %
Nursing and Health Professions 25 21%
Medicine and Dentistry 18 15%
Psychology 13 11%
Biochemistry, Genetics and Molecular Biology 10 8%
Neuroscience 6 5%
Other 19 16%
Unknown 30 25%

Attention Score in Context

This research output has an Altmetric Attention Score of 30. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 December 2019.
All research outputs
#902,019
of 19,153,137 outputs
Outputs from Molecular Autism
#98
of 614 outputs
Outputs of similar age
#22,322
of 291,194 outputs
Outputs of similar age from Molecular Autism
#1
of 1 outputs
Altmetric has tracked 19,153,137 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 614 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 28.9. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 291,194 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 1 others from the same source and published within six weeks on either side of this one. This one has scored higher than all of them