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A novel role for ezrin in breast cancer angio/lymphangiogenesis

Overview of attention for article published in Breast Cancer Research, September 2014
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Mentioned by

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1 X user
facebook
1 Facebook page

Citations

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38 Dimensions

Readers on

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38 Mendeley
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Title
A novel role for ezrin in breast cancer angio/lymphangiogenesis
Published in
Breast Cancer Research, September 2014
DOI 10.1186/s13058-014-0438-2
Pubmed ID
Authors

Abdi Ghaffari, Victoria Hoskin, Alvin Szeto, Maaike Hum, Navid Liaghati, Kanji Nakatsu, Yolanda Madarnas, Sandip Sengupta, Bruce E Elliott

Abstract

Recent evidence suggests that tumour lymphangiogenesis promotes lymph node metastasis, a major prognostic factor for survival of breast cancer patients. However, signaling mechanisms involved in tumour-induced lymphangiogenesis remain poorly understood. The expression of ezrin, a membrane cytoskeletal crosslinker and Src substrate, correlates with poor outcome in a diversity of cancers including breast. Furthermore, ezrin is essential in experimental invasion and metastasis models of breast cancer. Ezrin acts cooperatively with Src in the regulation of the Src-induced malignant phenotype and metastasis. However, it remains unclear if ezrin plays a role in Src-induced tumour angio/lymphangiogenesis.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 38 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 38 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 7 18%
Student > Doctoral Student 5 13%
Student > Ph. D. Student 5 13%
Student > Bachelor 4 11%
Student > Master 4 11%
Other 8 21%
Unknown 5 13%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 29%
Biochemistry, Genetics and Molecular Biology 9 24%
Medicine and Dentistry 8 21%
Pharmacology, Toxicology and Pharmaceutical Science 2 5%
Sports and Recreations 1 3%
Other 1 3%
Unknown 6 16%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 19 September 2014.
All research outputs
#19,944,091
of 25,373,627 outputs
Outputs from Breast Cancer Research
#1,654
of 2,052 outputs
Outputs of similar age
#179,015
of 260,155 outputs
Outputs of similar age from Breast Cancer Research
#26
of 44 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,052 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 12.2. This one is in the 16th percentile – i.e., 16% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 260,155 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 44 others from the same source and published within six weeks on either side of this one. This one is in the 34th percentile – i.e., 34% of its contemporaries scored the same or lower than it.