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Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice

Overview of attention for article published in Journal of Biomedical Science, August 2010
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Title
Cardiac and skeletal muscle abnormality in taurine transporter-knockout mice
Published in
Journal of Biomedical Science, August 2010
DOI 10.1186/1423-0127-17-s1-s20
Pubmed ID
Authors

Takashi Ito, Shohei Oishi, Mika Takai, Yasushi Kimura, Yoriko Uozumi, Yasushi Fujio, Stephen W Schaffer, Junichi Azuma

Abstract

Taurine, a sulfur-containing beta-amino acid, is highly contained in heart and skeletal muscle. Taurine has a variety of biological actions, such as ion movement, calcium handling and cytoprotection in the cardiac and skeletal muscles. Meanwhile, taurine deficiency leads various pathologies, including dilated cardiomyopathy, in cat and fox. However, the essential role of taurine depletion on pathogenesis has not been fully clarified. To address the physiological role of taurine in mammalian tissues, taurine transporter-(TauT-) knockout models were recently generated. TauTKO mice exhibited loss of body weight, abnormal cardiac function and the reduced exercise capacity with tissue taurine depletion. In this chapter, we summarize pathological profile and histological feature of heart and skeletal muscle in TauTKO mice.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 69 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 2 3%
Japan 1 1%
China 1 1%
Unknown 65 94%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 17%
Student > Bachelor 11 16%
Student > Master 9 13%
Researcher 8 12%
Professor > Associate Professor 5 7%
Other 13 19%
Unknown 11 16%
Readers by discipline Count As %
Medicine and Dentistry 15 22%
Agricultural and Biological Sciences 10 14%
Biochemistry, Genetics and Molecular Biology 9 13%
Pharmacology, Toxicology and Pharmaceutical Science 4 6%
Sports and Recreations 4 6%
Other 17 25%
Unknown 10 14%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2014.
All research outputs
#22,758,309
of 25,373,627 outputs
Outputs from Journal of Biomedical Science
#969
of 1,101 outputs
Outputs of similar age
#98,333
of 103,422 outputs
Outputs of similar age from Journal of Biomedical Science
#31
of 32 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,101 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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