Title |
The evolution of novel fungal genes from non-retroviral RNA viruses
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Published in |
BMC Biology, December 2009
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DOI | 10.1186/1741-7007-7-88 |
Pubmed ID | |
Authors |
Derek J Taylor, Jeremy Bruenn |
Abstract |
Endogenous derivatives of non-retroviral RNA viruses are thought to be absent or rare in eukaryotic genomes because integration of RNA viruses in host genomes is impossible without reverse transcription. However, such derivatives have been proposed for animals, plants and fungi, often based on surrogate bioinformatic evidence. At present, there is little known of the evolution and function of integrated non-retroviral RNA virus genes. Here, we provide direct evidence of integration by sequencing across host-virus gene boundaries and carry out phylogenetic analyses of fungal hosts and totivirids (dsRNA viruses of fungi and protozoans). Further, we examine functionality by tests of neutral evolution, comparison of residues that are necessary for viral capsid functioning and assays for transcripts, dsRNA and viral particles. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 3 | 3% |
Brazil | 3 | 3% |
Italy | 1 | 1% |
South Africa | 1 | 1% |
France | 1 | 1% |
Costa Rica | 1 | 1% |
Mexico | 1 | 1% |
Spain | 1 | 1% |
United States | 1 | 1% |
Other | 0 | 0% |
Unknown | 87 | 87% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 25 | 25% |
Student > Ph. D. Student | 22 | 22% |
Student > Master | 8 | 8% |
Student > Bachelor | 7 | 7% |
Professor | 6 | 6% |
Other | 17 | 17% |
Unknown | 15 | 15% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 52 | 52% |
Biochemistry, Genetics and Molecular Biology | 23 | 23% |
Social Sciences | 2 | 2% |
Chemistry | 2 | 2% |
Computer Science | 1 | 1% |
Other | 5 | 5% |
Unknown | 15 | 15% |