Title |
Development and application of an AllGlo probe-based qPCR assay for detecting knockdown resistance (kdr) mutations in Anopheles sinensis
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Published in |
Malaria Journal, September 2014
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DOI | 10.1186/1475-2875-13-379 |
Pubmed ID | |
Authors |
Liang Bai, Guo-ding Zhu, Hua-yun Zhou, Jian-xia Tang, Ju-lin Li, Sui Xu, Mei-hua Zhang, Li-nong Yao, Guang-quan Huang, Yong-bin Wang, Hong-wei Zhang, Si-bao Wang, Jun Cao, Qi Gao |
Abstract |
Anopheles sinensis is one of the most important malaria vectors in China and other Southeast Asian countries. High levels of resistance have been reported in this species due to the long-term use of insecticides, especially pyrethroids, for public health and agricultural purposes. Knockdown resistance (kdr) caused by a single base pair mutation in the gene encoding the sodium channel is strongly associated with pyrethroid insecticide resistance in many Anopheles mosquitoes. There are few methods currently available for detecting kdr mutations in An. sinensis. |
X Demographics
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Unknown | 1 | 100% |
Demographic breakdown
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
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Unknown | 23 | 96% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Bachelor | 6 | 25% |
Researcher | 4 | 17% |
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Student > Master | 2 | 8% |
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Other | 6 | 25% |
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