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Acute undifferentiated fever in India: a multicentre study of aetiology and diagnostic accuracy

Overview of attention for article published in BMC Infectious Diseases, October 2017
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (86th percentile)
  • High Attention Score compared to outputs of the same age and source (94th percentile)

Mentioned by

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1 news outlet
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5 X users
wikipedia
1 Wikipedia page

Citations

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72 Dimensions

Readers on

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231 Mendeley
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Title
Acute undifferentiated fever in India: a multicentre study of aetiology and diagnostic accuracy
Published in
BMC Infectious Diseases, October 2017
DOI 10.1186/s12879-017-2764-3
Pubmed ID
Authors

Kristine Mørch, Anand Manoharan, Sara Chandy, Novin Chacko, Gerardo Alvarez-Uria, Suvarna Patil, Anil Henry, Joel Nesaraj, Cijoy Kuriakose, Ashita Singh, Siby Kurian, Christel Gill Haanshuus, Nina Langeland, Bjørn Blomberg, George Vasanthan Antony, Dilip Mathai

Abstract

The objectives of this study were to determine the proportion of malaria, bacteraemia, scrub typhus, leptospirosis, chikungunya and dengue among hospitalized patients with acute undifferentiated fever in India, and to describe the performance of standard diagnostic methods. During April 2011-November 2012, 1564 patients aged ≥5 years with febrile illness for 2-14 days were consecutively included in an observational study at seven community hospitals in six states in India. Malaria microscopy, blood culture, Dengue rapid NS1 antigen and IgM Combo test, Leptospira IgM ELISA, Scrub typhus IgM ELISA and Chikungunya IgM ELISA were routinely performed at the hospitals. Second line testing, Dengue IgM capture ELISA (MAC-ELISA), Scrub typhus immunofluorescence (IFA), Leptospira Microscopic Agglutination Test (MAT), malaria PCR and malaria immunochromatographic rapid diagnostic test (RDT) Parahit Total™ were performed at the coordinating centre. Convalescence samples were not available. Case definitions were as follows: Leptospirosis: Positive ELISA and positive MAT. Scrub typhus: Positive ELISA and positive IFA. Dengue: Positive RDT and/or positive MAC-ELISA. Chikungunya: Positive ELISA. Bacteraemia: Growth in blood culture excluding those defined as contaminants. Malaria: Positive genus-specific PCR. Malaria was diagnosed in 17% (268/1564) and among these 54% had P. falciparum. Dengue was diagnosed in 16% (244/1564). Bacteraemia was found in 8% (124/1564), and among these Salmonella typhi or S. paratyphi constituted 35%. Scrub typhus was diagnosed in 10%, leptospirosis in 7% and chikungunya in 6%. Fulfilling more than one case definition was common, most frequent in chikungunya where 26% (25/98) also had positive dengue test. Malaria and dengue were the most common causes of fever in this study. A high overlap between case definitions probably reflects high prevalence of prior infections, cross reactivity and subclinical infections, rather than high prevalence of coinfections. Low accuracy of routine diagnostic tests should be taken into consideration when approaching the patient with acute undifferentiated fever in India.

X Demographics

X Demographics

The data shown below were collected from the profiles of 5 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 231 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 231 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 29 13%
Student > Postgraduate 25 11%
Researcher 22 10%
Student > Bachelor 22 10%
Other 18 8%
Other 44 19%
Unknown 71 31%
Readers by discipline Count As %
Medicine and Dentistry 55 24%
Immunology and Microbiology 19 8%
Nursing and Health Professions 16 7%
Agricultural and Biological Sciences 15 6%
Biochemistry, Genetics and Molecular Biology 14 6%
Other 33 14%
Unknown 79 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 14. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 29 December 2021.
All research outputs
#2,131,739
of 22,780,165 outputs
Outputs from BMC Infectious Diseases
#599
of 7,670 outputs
Outputs of similar age
#44,284
of 322,305 outputs
Outputs of similar age from BMC Infectious Diseases
#7
of 135 outputs
Altmetric has tracked 22,780,165 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 90th percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,670 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.6. This one has done particularly well, scoring higher than 92% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,305 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 135 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 94% of its contemporaries.