Title |
Antibiotic stewardship in the intensive care unit
|
---|---|
Published in |
Critical Care, August 2014
|
DOI | 10.1186/s13054-014-0480-6 |
Pubmed ID | |
Authors |
Charles-Edouard Luyt, Nicolas Bréchot, Jean-Louis Trouillet, Jean Chastre |
Abstract |
The rapid emergence and dissemination of antimicrobial-resistant microorganisms in ICUs worldwide constitute a problem of crisis dimensions. The root causes of this problem are multifactorial, but the core issues are clear. The emergence of antibiotic resistance is highly correlated with selective pressure resulting from inappropriate use of these drugs. Appropriate antibiotic stewardship in ICUs includes not only rapid identification and optimal treatment of bacterial infections in these critically ill patients, based on pharmacokinetic-pharmacodynamic characteristics, but also improving our ability to avoid administering unnecessary broad-spectrum antibiotics, shortening the duration of their administration, and reducing the numbers of patients receiving undue antibiotic therapy. Either we will be able to implement such a policy or we and our patients will face an uncontrollable surge of very difficult-to-treat pathogens. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Spain | 12 | 29% |
United Kingdom | 5 | 12% |
United States | 3 | 7% |
Canada | 1 | 2% |
Ecuador | 1 | 2% |
Argentina | 1 | 2% |
Israel | 1 | 2% |
Australia | 1 | 2% |
Georgia | 1 | 2% |
Other | 1 | 2% |
Unknown | 15 | 36% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 27 | 64% |
Practitioners (doctors, other healthcare professionals) | 6 | 14% |
Scientists | 5 | 12% |
Science communicators (journalists, bloggers, editors) | 4 | 10% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | <1% |
France | 1 | <1% |
Unknown | 600 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 110 | 18% |
Student > Master | 91 | 15% |
Student > Ph. D. Student | 55 | 9% |
Researcher | 44 | 7% |
Student > Postgraduate | 32 | 5% |
Other | 84 | 14% |
Unknown | 186 | 31% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 123 | 20% |
Biochemistry, Genetics and Molecular Biology | 69 | 11% |
Pharmacology, Toxicology and Pharmaceutical Science | 65 | 11% |
Agricultural and Biological Sciences | 40 | 7% |
Immunology and Microbiology | 28 | 5% |
Other | 77 | 13% |
Unknown | 200 | 33% |