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Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis

Overview of attention for article published in Arthritis Research & Therapy, January 2014
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3 X users

Citations

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90 Dimensions

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68 Mendeley
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Title
Expression and function of visfatin (Nampt), an adipokine-enzyme involved in inflammatory pathways of osteoarthritis
Published in
Arthritis Research & Therapy, January 2014
DOI 10.1186/ar4467
Pubmed ID
Authors

Marie-Charlotte Laiguillon, Xavier Houard, Carole Bougault, Marjolaine Gosset, Geoffroy Nourissat, Alain Sautet, Claire Jacques, Francis Berenbaum, Jérémie Sellam

Abstract

Visfatin is an adipokine that may be involved in intertissular joint communication in osteoarthritis (OA). With a homodimeric conformation, it exerts nicotinamide phosphoribosyltransferase (Nampt) enzymatic activity, essential for nicotinamide adenine dinucleotide biosynthesis. We examined the tissular origin and conformation of visfatin/Nampt in human OA joints and investigated the role of visfatin/Nampt in chondrocytes and osteoblasts by studying Nampt enzymatic activity.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 68 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Italy 2 3%
United Kingdom 1 1%
France 1 1%
Saudi Arabia 1 1%
Unknown 63 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 12 18%
Researcher 9 13%
Student > Doctoral Student 7 10%
Student > Bachelor 6 9%
Student > Master 5 7%
Other 16 24%
Unknown 13 19%
Readers by discipline Count As %
Medicine and Dentistry 18 26%
Agricultural and Biological Sciences 12 18%
Biochemistry, Genetics and Molecular Biology 9 13%
Pharmacology, Toxicology and Pharmaceutical Science 3 4%
Nursing and Health Professions 2 3%
Other 8 12%
Unknown 16 24%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 September 2015.
All research outputs
#15,998,913
of 25,394,764 outputs
Outputs from Arthritis Research & Therapy
#2,332
of 3,382 outputs
Outputs of similar age
#186,111
of 322,499 outputs
Outputs of similar age from Arthritis Research & Therapy
#31
of 63 outputs
Altmetric has tracked 25,394,764 research outputs across all sources so far. This one is in the 36th percentile – i.e., 36% of other outputs scored the same or lower than it.
So far Altmetric has tracked 3,382 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one is in the 30th percentile – i.e., 30% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 322,499 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 42nd percentile – i.e., 42% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 63 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 50% of its contemporaries.