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Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints

Overview of attention for article published in Arthritis Research & Therapy, September 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (93rd percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

Mentioned by

news
1 news outlet
twitter
14 X users
facebook
10 Facebook pages

Citations

dimensions_citation
26 Dimensions

Readers on

mendeley
80 Mendeley
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Title
Tapping into the endocannabinoid system to ameliorate acute inflammatory flares and associated pain in mouse knee joints
Published in
Arthritis Research & Therapy, September 2014
DOI 10.1186/s13075-014-0437-9
Pubmed ID
Authors

Eugene Krustev, Allison Reid, Jason J McDougall

Abstract

During the progression of rheumatoid arthritis (RA), there are frequent but intermittent flares in which the joint becomes acutely inflamed and painful. Although a number of drug therapies are currently used to treat RA, their effectiveness is variable and side effects are common. Endocannabinoids have the potential to ameliorate joint pain and inflammation, but these beneficial effects are limited by their rapid degradation. One enzyme responsible for endocannabinoid breakdown is fatty acid amide hydrolase (FAAH). The present study examined whether URB597, a potent and selective FAAH inhibitor, could alter inflammation and pain in a mouse model of acute synovitis.

X Demographics

X Demographics

The data shown below were collected from the profiles of 14 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 80 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Canada 2 3%
Germany 1 1%
United States 1 1%
Unknown 76 95%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 19 24%
Student > Ph. D. Student 14 18%
Student > Master 10 13%
Researcher 6 8%
Other 5 6%
Other 11 14%
Unknown 15 19%
Readers by discipline Count As %
Medicine and Dentistry 19 24%
Agricultural and Biological Sciences 8 10%
Pharmacology, Toxicology and Pharmaceutical Science 7 9%
Biochemistry, Genetics and Molecular Biology 5 6%
Neuroscience 5 6%
Other 15 19%
Unknown 21 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 22. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 31 August 2017.
All research outputs
#1,682,556
of 25,373,627 outputs
Outputs from Arthritis Research & Therapy
#232
of 3,381 outputs
Outputs of similar age
#18,271
of 263,753 outputs
Outputs of similar age from Arthritis Research & Therapy
#2
of 49 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 93rd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 3,381 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.2. This one has done particularly well, scoring higher than 93% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 263,753 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 93% of its contemporaries.
We're also able to compare this research output to 49 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.