Title |
Effects of vitamin D in the elderly population: current status and perspectives
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Published in |
Archives of Public Health, September 2014
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DOI | 10.1186/2049-3258-72-32 |
Pubmed ID | |
Authors |
Olivier Bruyère, Etienne Cavalier, Jean-Claude Souberbielle, Heike A Bischoff-Ferrari, Charlotte Beaudart, Fanny Buckinx, Jean-Yves Reginster, René Rizzoli |
Abstract |
Besides its well-known effect on bone metabolism, recent researches suggest that vitamin D may also play a role in the muscular, immune, endocrine, and central nervous systems. Double-blind RCTs support vitamin D supplementation at a dose of 800 IU per day for the prevention of falls and fractures in the senior population. Ecological, case-control and cohort studies have suggested that high vitamin D levels were associated with a reduced risk of autoimmune diseases, type 2 diabetes, cardio-vascular diseases and cancer but large clinical trials are lacking today to provide solid evidence of a vitamin D benefit beyond bone health. At last, the optimal dose, route of administration, dosing interval and duration of vitamin D supplementation at a specific target dose beyond the prevention of vitamin D deficiency need to be further investigated. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United Kingdom | 1 | 20% |
Unknown | 4 | 80% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 4 | 80% |
Practitioners (doctors, other healthcare professionals) | 1 | 20% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
New Zealand | 1 | <1% |
Spain | 1 | <1% |
Unknown | 116 | 98% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 15 | 13% |
Student > Master | 13 | 11% |
Researcher | 12 | 10% |
Student > Ph. D. Student | 12 | 10% |
Other | 9 | 8% |
Other | 25 | 21% |
Unknown | 32 | 27% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 49 | 42% |
Agricultural and Biological Sciences | 7 | 6% |
Nursing and Health Professions | 5 | 4% |
Pharmacology, Toxicology and Pharmaceutical Science | 4 | 3% |
Biochemistry, Genetics and Molecular Biology | 4 | 3% |
Other | 9 | 8% |
Unknown | 40 | 34% |