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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Vitamin D deficiency down-regulates Notch pathway contributing to skeletal muscle atrophy in old wistar rats
|
|---|---|
| Published in |
Nutrition & Metabolism, September 2014
|
| DOI | 10.1186/1743-7075-11-47 |
| Pubmed ID | |
| Authors |
Carla Domingues-Faria, Audrey Chanet, Jérôme Salles, Alexandre Berry, Christophe Giraudet, Véronique Patrac, Philippe Denis, Katia Bouton, Nicolas Goncalves-Mendes, Marie-Paule Vasson, Yves Boirie, Stéphane Walrand |
| Abstract |
The diminished ability of aged muscle to self-repair is a factor behind sarcopenia and contributes to muscle atrophy. Muscle repair depends on satellite cells whose pool size is diminished with aging. A reduction in Notch pathway activity may explain the age-related decrease in satellite cell proliferation, as this pathway has been implicated in satellite cell self-renewal. Skeletal muscle is a target of vitamin D which modulates muscle cell proliferation and differentiation in vitro and stimulates muscle regeneration in vivo. Vitamin D status is positively correlated to muscle strength/function, and elderly populations develop a vitamin D deficiency. The aim of this study was to evaluate how vitamin D deficiency induces skeletal muscle atrophy in old rats through a reduction in Notch pathway activity and proliferation potential in muscle. |
X Demographics
The data shown below were collected from the profiles of 11 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 5 | 45% |
| United States | 3 | 27% |
| Norway | 1 | 9% |
| Unknown | 2 | 18% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 6 | 55% |
| Scientists | 5 | 45% |
Mendeley readers
The data shown below were compiled from readership statistics for 78 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Brazil | 2 | 3% |
| United Kingdom | 1 | 1% |
| Denmark | 1 | 1% |
| Spain | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 72 | 92% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 21 | 27% |
| Student > Master | 21 | 27% |
| Student > Bachelor | 10 | 13% |
| Researcher | 6 | 8% |
| Professor > Associate Professor | 4 | 5% |
| Other | 10 | 13% |
| Unknown | 6 | 8% |
| Readers by discipline | Count | As % |
|---|---|---|
| Biochemistry, Genetics and Molecular Biology | 17 | 22% |
| Agricultural and Biological Sciences | 17 | 22% |
| Medicine and Dentistry | 13 | 17% |
| Sports and Recreations | 9 | 12% |
| Nursing and Health Professions | 4 | 5% |
| Other | 6 | 8% |
| Unknown | 12 | 15% |
Attention Score in Context
This research output has an Altmetric Attention Score of 7. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 November 2014.
All research outputs
#4,166,396
of 22,764,165 outputs
Outputs from Nutrition & Metabolism
#345
of 945 outputs
Outputs of similar age
#46,482
of 252,706 outputs
Outputs of similar age from Nutrition & Metabolism
#6
of 10 outputs
Altmetric has tracked 22,764,165 research outputs across all sources so far. Compared to these this one has done well and is in the 80th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 945 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 25.3. This one has gotten more attention than average, scoring higher than 62% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 252,706 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 80% of its contemporaries.
We're also able to compare this research output to 10 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.