↓ Skip to main content

Bidens pilosa Ethylene acetate extract can protect against L-NAME-induced hypertension on rats

Overview of attention for article published in BMC Complementary and Alternative Medicine, October 2017
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Good Attention Score compared to outputs of the same age and source (72nd percentile)

Mentioned by

blogs
1 blog
twitter
1 tweeter

Citations

dimensions_citation
25 Dimensions

Readers on

mendeley
58 Mendeley
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Bidens pilosa Ethylene acetate extract can protect against L-NAME-induced hypertension on rats
Published in
BMC Complementary and Alternative Medicine, October 2017
DOI 10.1186/s12906-017-1972-0
Pubmed ID
Authors

Danielle Claude Bilanda, Paul Désiré D. Dzeufiet, Léontine Kouakep, Bibi Farouck O. Aboubakar, Léonard Tedong, Pierre Kamtchouing, Théophile Dimo

Abstract

Essential hypertension is mainly caused by endothelial dysfunction which results from nitric oxide (NO) deficiency. The present study was design to evaluate the protective effect of Bidens pilosa ethylene acetate extract (Bp) on L-NAME induced hypertension and oxidative stress in rats. Male Wistar rats were used to induce hypertension by the administration of L-NAME (a non-pecific nitric oxide inhibitor) (50 mg/kg/day). The others groups were receiving concomitantly L-NAME plus Bp extract (75 and 150 mg/kg/day) or losartan (25 mg/kg/day). All the treatments were given orally for 4 weeks. At the end of the treatment, the hemodynamic parameters were recorded using the direct cannulation method. The effects of the extract on lipid profile, kidney and liver functions as well as oxidative stress markers were evaluated by colorimetric method. Results were expressed as the mean ± SEM. The difference between the groups was compared using one-way analysis of variance (ANOVA) followed by the Duncan's post hoc test. Animals receiving L-NAME presented high blood pressure, normal heart rate and lipid profile as well as NO depletion, liver and kidney injuries and oxidative stress. The concomitant treatment with L-NAME and Bp or losartan succeeded to prevent the raised of blood pressure and all the other injuries without affecting the heart rate. These results confirm the antihypertensive effects of Bidens pilosa and highlight its protective properties in L-NAME model of hypertension in rat, probably due to the presence of Quercetin 3,3 '-dimethyl ether 7-0-β-D-glucopyranoside.

Twitter Demographics

The data shown below were collected from the profile of 1 tweeter who shared this research output. Click here to find out more about how the information was compiled.

Mendeley readers

The data shown below were compiled from readership statistics for 58 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 58 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 12%
Student > Bachelor 7 12%
Student > Master 6 10%
Student > Postgraduate 4 7%
Student > Doctoral Student 3 5%
Other 11 19%
Unknown 20 34%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 14 24%
Biochemistry, Genetics and Molecular Biology 4 7%
Agricultural and Biological Sciences 3 5%
Computer Science 3 5%
Unspecified 3 5%
Other 13 22%
Unknown 18 31%

Attention Score in Context

This research output has an Altmetric Attention Score of 8. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 October 2017.
All research outputs
#1,782,544
of 12,037,162 outputs
Outputs from BMC Complementary and Alternative Medicine
#427
of 2,456 outputs
Outputs of similar age
#59,932
of 274,237 outputs
Outputs of similar age from BMC Complementary and Alternative Medicine
#2
of 11 outputs
Altmetric has tracked 12,037,162 research outputs across all sources so far. Compared to these this one has done well and is in the 85th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,456 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.7. This one has done well, scoring higher than 82% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 274,237 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 11 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.