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Comparative analysis of miRNA expression during the development of insects of different metamorphosis modes and germ-band types

Overview of attention for article published in BMC Genomics, October 2017
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  • Above-average Attention Score compared to outputs of the same age and source (58th percentile)

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7 tweeters

Citations

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26 Dimensions

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40 Mendeley
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Title
Comparative analysis of miRNA expression during the development of insects of different metamorphosis modes and germ-band types
Published in
BMC Genomics, October 2017
DOI 10.1186/s12864-017-4177-5
Pubmed ID
Authors

Guillem Ylla, Maria-Dolors Piulachs, Xavier Belles

Abstract

Do miRNAs contribute to specify the germ-band type and the body structure in the insect embryo? Our goal was to address that issue by studying the changes in miRNA expression along the ontogeny of the German cockroach Blattella germanica, which is a short germ-band and hemimetabolan species. We sequenced small RNA libraries representing 11 developmental stages of B. germanica ontogeny (with especial emphasis on embryogenesis) and the changes in miRNA expression were examined. Data were compared with equivalent data for two long germ-band holometabolan species Drosophila melanogaster and Drosophila virilis, and the short germ-band holometabolan species Tribolium castaneum. The identification of B. germanica embryo small RNA sequences unveiled miRNAs not detected in previous studies, such as those of the MIR-309 family and 54 novel miRNAs. Four main waves of miRNA expression were recognized (with most miRNA changes occurring during the embryonic stages): the first from day 0 to day 1 of embryogenesis, the second during mid-embryogenesis (days 0-6), the third (with an acute expression peak) on day 2 of embryonic development, and the fourth during post-embryonic development. The second wave defined the boundaries of maternal-to-zygotic transition, with maternal mRNAs being cleared, presumably by Mir-309 and associated scavenger miRNAs. miRNAs follow well-defined patterns of expression over hemimetabolan ontogeny, patterns that are more diverse during embryonic development than during the nymphal stages. The results suggest that miRNAs play important roles in the developmental transitions between the embryonic stages of development (starting with maternal loading), during which they might influence the germ-band type and metamorphosis mode.

Twitter Demographics

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Mendeley readers

The data shown below were compiled from readership statistics for 40 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 40 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 25%
Researcher 7 18%
Student > Bachelor 6 15%
Student > Master 4 10%
Student > Doctoral Student 3 8%
Other 6 15%
Unknown 4 10%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 40%
Biochemistry, Genetics and Molecular Biology 15 38%
Computer Science 1 3%
Immunology and Microbiology 1 3%
Engineering 1 3%
Other 0 0%
Unknown 6 15%

Attention Score in Context

This research output has an Altmetric Attention Score of 5. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 07 December 2017.
All research outputs
#4,345,827
of 15,985,195 outputs
Outputs from BMC Genomics
#2,241
of 8,890 outputs
Outputs of similar age
#87,094
of 282,238 outputs
Outputs of similar age from BMC Genomics
#12
of 29 outputs
Altmetric has tracked 15,985,195 research outputs across all sources so far. This one has received more attention than most of these and is in the 72nd percentile.
So far Altmetric has tracked 8,890 research outputs from this source. They receive a mean Attention Score of 4.3. This one has gotten more attention than average, scoring higher than 74% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 282,238 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 68% of its contemporaries.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 58% of its contemporaries.