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Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling

Overview of attention for article published in BMC Cancer, October 2014
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (83rd percentile)
  • High Attention Score compared to outputs of the same age and source (89th percentile)

Mentioned by

blogs
1 blog
twitter
2 X users

Citations

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48 Dimensions

Readers on

mendeley
56 Mendeley
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Title
Malignant stroma increases luminal breast cancer cell proliferation and angiogenesis through platelet-derived growth factor signaling
Published in
BMC Cancer, October 2014
DOI 10.1186/1471-2407-14-735
Pubmed ID
Authors

Mauricio P Pinto, Wendy W Dye, Britta M Jacobsen, Kathryn B Horwitz

Abstract

Luminal, estrogen receptor-positive breast cancers represent more than 70% of cases. Despite initial good prognoses one third of Luminal cancers eventually recur locally or at distant sites and exhibit hormone resistance. Here we demonstrate that factors elaborated by malignant stromal cells can induce Luminal tumor cells proliferation and promote angiogenesis and hormone independence. We recently isolated a malignant mouse mammary gland stromal cell line named BJ3Z that increases proliferation and angiogenesis in estrogen-free xenografted Luminal MCF-7 breast cancer cells.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 56 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 56 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 20%
Student > Bachelor 9 16%
Researcher 8 14%
Student > Doctoral Student 4 7%
Student > Master 4 7%
Other 7 13%
Unknown 13 23%
Readers by discipline Count As %
Medicine and Dentistry 11 20%
Biochemistry, Genetics and Molecular Biology 10 18%
Agricultural and Biological Sciences 8 14%
Engineering 5 9%
Pharmacology, Toxicology and Pharmaceutical Science 2 4%
Other 3 5%
Unknown 17 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 October 2014.
All research outputs
#3,587,694
of 22,765,347 outputs
Outputs from BMC Cancer
#822
of 8,278 outputs
Outputs of similar age
#40,855
of 253,597 outputs
Outputs of similar age from BMC Cancer
#15
of 145 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 8,278 research outputs from this source. They receive a mean Attention Score of 4.3. This one has done particularly well, scoring higher than 90% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 253,597 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 145 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 89% of its contemporaries.