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Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer

Overview of attention for article published in Molecular Cancer, August 2014
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About this Attention Score

  • Above-average Attention Score compared to outputs of the same age (51st percentile)
  • Above-average Attention Score compared to outputs of the same age and source (57th percentile)

Mentioned by

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1 X user
peer_reviews
1 peer review site

Citations

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48 Dimensions

Readers on

mendeley
57 Mendeley
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Title
Thymoquinone-induced conformational changes of PAK1 interrupt prosurvival MEK-ERK signaling in colorectal cancer
Published in
Molecular Cancer, August 2014
DOI 10.1186/1476-4598-13-201
Pubmed ID
Authors

Chirine El-Baba, Vijayalakshmi Mahadevan, Fabian B Fahlbusch, Suma Mohan S, Tilman T Rau, Hala Gali-Muhtasib, Regine Schneider-Stock

Abstract

Thymoquinone (TQ) was shown to reduce tumor growth in several cancer models both in vitro and in vivo. So far only a few targets of TQ, including protein kinases have been identified. Considering that kinases are promising candidates for targeted anticancer therapy, we studied the complex kinase network regulated by TQ.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 57 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 56 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 11 19%
Student > Master 6 11%
Student > Doctoral Student 6 11%
Researcher 6 11%
Student > Bachelor 5 9%
Other 8 14%
Unknown 15 26%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 9 16%
Medicine and Dentistry 7 12%
Agricultural and Biological Sciences 6 11%
Pharmacology, Toxicology and Pharmaceutical Science 5 9%
Chemistry 3 5%
Other 9 16%
Unknown 18 32%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 14 December 2016.
All research outputs
#13,413,791
of 22,765,347 outputs
Outputs from Molecular Cancer
#831
of 1,719 outputs
Outputs of similar age
#111,752
of 236,208 outputs
Outputs of similar age from Molecular Cancer
#19
of 45 outputs
Altmetric has tracked 22,765,347 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 1,719 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one is in the 49th percentile – i.e., 49% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 236,208 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.
We're also able to compare this research output to 45 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 57% of its contemporaries.